Dendritic folate rosettes as ion channels in lipid bilayers.
Dendritic folate rosettes as ion channels in lipid bilayers.
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DOI:
10.1021/ja058157k
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发表时间:
2006-01
影响因子:
15
通讯作者:
N. Sakai;Y. Kamikawa;M. Nishii;Toru Matsuoka;Takashi Kato;S. Matile
中科院分区:
文献类型:
--
作者:
N. Sakai;Y. Kamikawa;M. Nishii;Toru Matsuoka;Takashi Kato;S. Matile
The self-assembly of folate dendrimers into pi-stacked supramolecular rosettes is shown to produce ion channels in planar and spherical lipid bilayer membranes. The found ion channels are small, quite homogeneous, long-lived, ohmic, cation selective (Eisenman I), and blockable by the permeant cation.