Respiratory symptoms in urban Hispanic and non-Hispanic white women
Respiratory symptoms in urban Hispanic and non-Hispanic white women
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DOI：
10.1164/ajrccm.153.4.8616555
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发表时间：
1996-04-01
影响因子：
24.7
通讯作者：
Tager, IB
中科院分区：
文献类型：
--
作者：
David, MMA;Hanrahan, JP;Tager, IB
在马萨诸塞州东波士顿进行的一项基于人群的研究中，对475名非希帕尼克（NH）白色和371名西班牙裔孕妇进行了喘息综合征（包括哮喘）的患病率和预测因素的研究。在妊娠早期通过问卷调查确定呼吸道症状和危险因素。西班牙裔和NH白色女性的年龄相似（平均值+/- SD，26 +/- 5岁），但西班牙裔报告受教育程度较低（30%比50%完成高中学业），家庭宠物的频率较低（4%比47%），父母哮喘的频率较低（6%比12%）。西班牙裔吸烟率明显低于新罕布什尔州白人，无论是在患病率（8比50%）还是当前吸烟者每天吸烟数量（12 +/- 9比22 +/- 10; p < 0.0001）方面。西班牙裔报告的医生诊断的哮喘（6对12%），持续性喘息（5对19%），以及持续性喘息或哮喘（11对30%）的频率低于NH白人。在多变量分析中，主动吸烟和父母哮喘史与喘息综合征的相关性最强。当这两个因素以及教育水平、家庭宠物的存在和身高调整的FEV（1）得到控制时，西班牙裔人与NH白人相比，哮喘（比值比[OR] 0.71; 95%置信区间[CI]，0.37-1.37）和持续喘息（OR 0.48; 95% CI，0.25-0.95）的风险仍然较低。这些结果表明，慢性喘息综合征是常见的年轻城市妇女，并与积极吸烟和父母的哮喘史。生活在美国城市环境中的中美洲和南美洲的西班牙裔妇女患这些疾病的风险可能低于NH白色妇女，与来自波多黎各的妇女相反。
The prevalence and predictors of wheeze syndromes, including asthma, were examined among 475 non-Hipanic (NH) white and 371 Hispanic pregnant women enrolled in a population-based study in East Boston, Massachusetts. Respiratory symptoms and risk factors were ascertained by questionnaire early in pregnancy. Hispanic and NH white women were of similar age (mean +/- SD, 26 +/- 5 yr), but Hispanics reported less schooling (30 versus 50% completed high school), a lower frequency of household pets (4 versus 47%), and a lower frequency of parental asthma (6 versus 12%). Hispanics smoked significantly less than NH whites did, both in prevalence (8 versus 50%) and number of cigarettes per day among current smokers (12 +/- 9 versus 22 +/- 10; p < 0.0001). Hispanics reported a lower frequency than NH whites did of doctor-diagnosed asthma (6 versus 12%), persistent wheeze (5 versus 19%), and either persistent wheeze or asthma (11 versus 30%). In multivariate analysis, active cigarette smoking and parental history of asthma were associated most strongly with wheeze syndromes. When these two factors as well as educational level, presence of household pets, and height(2)-adjusted FEV(1) were controlled, Hispanics remained at lower risk of asthma (odds ratio [OR] 0.71; 95% confidence interval [CI], 0.37-1.37) and persistent wheeze (OR 0.48; 95% CI, 0.25-0.95) than NH whites. These results suggest that chronic wheeze syndromes are common among young urban women and are associated with both active smoking and a parental history of asthma. Hispanic women from Central and South America living in urban environments in the United States may be at less risk for these conditions than NH white women, in contrast to those from Puerto Rico.