Feasibility of Real Time Medication Monitoring Among HIV Infected and TB Patients in a Resource-Limited Setting

Feasibility of Real Time Medication Monitoring Among HIV Infected and TB Patients in a Resource-Limited Setting
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DOI:
10.1007/s10461-015-1254-0
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发表时间:
2016-05-01
期刊:
影响因子:
4.4
通讯作者:
Kibiki, Gibson S.
Kibiki, Gibson S.
中科院分区:
医学2区
文献类型:
--
作者:
de Sumari-de Boer, I. Marion;van den Boogaard, Jossy;Kibiki, Gibson S.

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艾滋病毒感染者和结核病(TB)患者需要高水平的治疗依从性,以实现最佳治疗效果。我们进行了一项试点研究真实的时间用药监测(RTMM)在资源有限的设置。我们从坦桑尼亚的基利曼哈罗招募了5名HIV感染者和5名TB患者。他们使用RTMM服用药物。当设备没有按时打开时,患者会收到提醒短信。3个月后,我们采访了病人。6例患者(60%)达到> 95%的依从性。1104次摄入中有922次(84%)按时摄入。由于移动的网络不稳定,发送了500份提醒(45%),其中202份(40%)不正确。9名患者发现该设备有帮助,9名患者提到它可以保证药物安全。6名患者报告尺寸过大。5名患者提到他们收到了不正确的提醒。该装置被认为是有用的基利曼哈罗。设备的优化应考虑网络连接和设备的大小。
HIV infected and tuberculosis (TB) patients need high levels of treatment adherence to achieve optimal treatment outcomes. We conducted a pilot-study on real time medication monitoring (RTMM) in a resource-limited setting. We enrolled five HIV infected and five TB patients from Kilimanjaro, Tanzania. They took their medication using RTMM. When the device was not opened on time, patients received a reminder SMS. After 3 months, we interviewed patients. Six patients (60 %) reached adherence of > 95 %. Nine-hundred-twenty-two of 1104 intakes (84 %) were on time. Five-hundred reminders (45 %) were sent, of which 202 (40 %) were incorrect, because of an unstable mobile network. Nine patients found the device helpful and nine mentioned it keeps medication safe. Six patients reported that the size was too big. Five patients mentioned they received incorrect reminders. The device is considered useful in Kilimanjaro. Optimization of the device should consider network connectivity and the size of the device.