Characterization of aza-arenes in basic organic portion of suspended particulate matter
Characterization of aza-arenes in basic organic portion of suspended particulate matter
复制标题
悬浮颗粒物质基本有机部分中氮杂芳烃的表征
DOI：
10.1021/es60129a007
复制
发表时间：
1977
影响因子：
11.4
通讯作者：
D. Hoffmann
中科院分区：
文献类型：
--
作者：
M. Dong;D. Locke;D. Hoffmann
氮杂芳烃是由含电视的有机物不完全燃烧形成的微量污染物，存在于纽约市悬浮颗粒物的基本部分中。我们描述了一种利用萃取、溶剂分配和一系列色谱分离的分离技术。用苯/甲醇对过滤器上收集的颗粒物进行索氏提取，并通过HPLC对从可提取物中得到的碱性馏分进行预分级。通过 GC/MS 和 HPLC 进一步分离亚组分，然后进行光谱鉴定。这种方法可以明确识别 20 多种氮杂芳烃和其他以前未识别的 N-碱基，并深入了解基本部分的复杂性。定量数据还显示，该馏分中含有意想不到的大量喹啉、异喹啉及其烷基衍生物。多核氮杂杂环烃（氮杂芳烃）的分析方法在过去受到了一些关注，因为其中许多化合物，如二苯并 (a, j) 吖啶、二苯 (a, h) 吖啶和一些烷基苯并吖啶，是已知的动物致癌物(1, 2)。最近，
Aza-arenes, formed as trace pollutants by incomplete combustion of TV-containing organic matter, are found in the basic fraction of New York City’s suspended particulate matter. We describe an isolating technique utilizing extrac-tion, solvent partitioning, and a sequence of chromatographic separations. Particulate matter collected on filters is Soxhlet extracted with benzene/methanol, and the basic fraction de-rived from the extractable matter is prefractionated by HPLC. The subfractions are further separated by GC/MS and HPLC, followed by spectroscopic identification. This approach leads to the unambiguous identification of over 20 aza-arenes and other N-bases previously unidentified, andgives insight into the complexity of the basic fraction. Quantitative data also show an unanticipated abundance of quinolines, isoquinolines, and their alkyl derivatives in the fraction.Analytical methods for polynuclear aza-heterocyclic hydrocarbons (aza-arenes) have received some attention in the past, since a number of these compounds, such as dibenz (a, j) acridine, dibenz (a, h) acridine, and some alkyl ben-zacridines, are known animal carcinogens (1, 2). Recently,