Voxel-based morphometry and its application to movement disorders.
Voxel-based morphometry and its application to movement disorders.
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DOI：
10.1016/s1353-8020(08)70039-7
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发表时间：
2007
影响因子：
4.1
通讯作者：
J. Whitwell;K. Josephs
中科院分区：
文献类型：
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作者：
J. Whitwell;K. Josephs
基于体素的形态测定法（VBM）是一种自动化技术，用于评估两组受试者之间MRI上区域性灰质和白色萎缩的模式。VBM已用于评估运动障碍受试者的局部萎缩模式。这些研究已经证明了每种疾病中区域损失的特定模式，比较了不同的运动障碍以寻找可能在诊断上有用的差异，并将这些受试者的损失区域与认知和运动缺陷相关联。本文将回顾这些研究的结果，并讨论VBM在运动障碍中的作用。
Voxel-based morphometry (VBM) is an automated technique that assesses patterns of regional grey and white matter atrophy on MRI between two groups of subjects. VBM has been used to assess patterns of regional atrophy in subjects with movement disorders. These studies have demonstrated specific patterns of regional loss in each disorder, compared different movement disorders to look for differences that could be diagnostically useful, and have correlated regions of loss to cognitive and motor deficits in these subjects. This article will review the findings of these studies and discuss the role of VBM in movement disorders.