Age of sitting unsupported and independent walking in very low birth weight preterm infants with normal motor development at 2 years
Age of sitting unsupported and independent walking in very low birth weight preterm infants with normal motor development at 2 years
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DOI：
10.1111/j.1651-2227.2009.01475.x
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发表时间：
2009-11-01
期刊：
影响因子：
3.8
通讯作者：
Lora Pablos, D.
中科院分区：
文献类型：
--
作者：
Marin Gabriel, M. A.;Pallas Alonso, C. R.;Lora Pablos, D.
目的：本研究的目的是（i）确定出生体重低于1500 g（极低出生体重，VLBW）的早产儿无支撑和独立行走的年龄;（ii）估计VLBW儿童与参考人群之间的差异;（iii）估计临床特征与晚期坐立和行走年龄之间的相关性。世界卫生组织（WHO）运动发育研究人群用作参考。这两种技能的年龄是通过与父母的访谈确定的。在适当的情况下，采用t检验、方差分析和Bonferroni调整对平均值进行比较。结果：694例患者符合纳入标准; 50%的VLBW在7 m矫正年龄（CA）时坐着，在13 m CA时行走。与对照组（6 +/-1.1和12.1 +/- 1.8 m）相比，两种运动技能的获得时间较晚（7.3 +/-1.5和13.6 +/- 2.8 m）。出生时体重或头围低于第10百分位数或支气管肺发育不良的存在与延迟收购的两个skills.Conclusion：非常低出生体重儿通常坐在不支持，走晚于足月儿。描述不同类别婴儿（胎龄、出生体重和其他决定因素）的里程碑获取参考值的表格可能有助于为获得可用资源的决策过程提供信息。
Aims:The aims of this study is to (i) determine the age of sitting unsupported and independent walking in preterm infants with birth weight under 1500 g (very low birth weight, VLBW); (ii) estimate differences between VLBW children and a reference population and (iii) estimate the association between clinical characteristics and late age at sitting and walking.Methods:A longitudinal study was conducted of a cohort of 876 children with VLBW. The World Health Organization (WHO) motor development study population was used as a reference. Ages for both skills were established by interview with parents. Means were compared with t-test, ANOVA and Bonferroni adjustment where appropriate.Results:The inclusion criteria were complied with 694 patients; 50% of VLBW sat at 7 m corrected age (CA) and walked at 13 m CA. Both motor skills were acquired later (7.3 +/- 1.5 and 13.6 +/- 2.8 m) compared with the control group (6 +/- 1.1 and 12.1 +/- 1.8 m). Weight or head circumference at birth below the 10th percentile or the presence of bronchopulmonary dysplasia were associated with delayed acquisition of both skills.Conclusion:Very low birth weight infants typically sit unsupported and walk later than term infants. Tables describing reference values for milestones acquisition for different categories of infants (gestational age, birth weight and other determinants) may contribute to inform the decision making process on access to available resources.