Outcomes Following In-Hospital Cardiopulmonary Resuscitation in People Receiving Maintenance Dialysis.

Outcomes Following In-Hospital Cardiopulmonary Resuscitation in People Receiving Maintenance Dialysis.
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DOI:
10.1016/j.xkme.2021.08.014
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发表时间:
2022-01
期刊:
影响因子:
3.9
通讯作者:
Fiscella KA
Fiscella KA
中科院分区:
其他
文献类型:
--
作者:
Saeed F;Murad HF;Wing RE;Li J;Schold JD;Fiscella KA

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先前显示透析人群心肺复苏(CPR)结局较差的研究主要来自索赔数据,并且由于缺乏CPR事件的详细表征而受到一定限制。我们旨在分析接受维持性透析的个体的CPR相关结局。回顾性病历审查。使用来自单一学术医疗保健系统的电子病历,我们确定了2006年至2014年期间接受维持性透析的所有住院成人患者,这些患者接受了院内CPR。初步院内心肺复苏总生存率,心肺复苏术失败的预测因子,首次存活者在同一住院期间死亡的预测因子,出院回家状态的预测因子。我们提供了研究变量的描述性统计量,并使用t检验、χ2检验或Fisher精确检验来比较组间差异。我们建立了多变量逻辑回归模型来检验CPR相关的结果。共有184例患者接受了院内CPR:51例(28%)在最初的CPR事件中没有存活,77例CPR幸存者在同一住院期间死亡(额外42%)(总死亡率70%)。只有18例(10%)出院回家,其余32例(17%)出院到康复机构或疗养院。在多变量模型中,CPR持续时间是CPR失败的唯一预测因素(OR,1.41; 95%CI,1.24-1.61; P < 0.001)。在首次CPR事件后同一住院期间死亡的预测因素是CPR持续时间(OR,1.15; 95%CI,1.04-1.27; P = 0.007)和年龄较大(OR,1.64; 95%CI,1.23-2.2; P < 0.001)。老年人出院回家的几率也较低(OR,0.25; 95%CI,0.11-0.54; P < 0.001)。回顾性研究设计,单中心研究,无功能状态信息。接受维持性透析的患者在院内CPR后死亡率很高,只有10%的患者出院回家。这些数据可以帮助临床医生提供有用的预后信息,同时参与护理对话的目标。
Previous studies showing poor cardiopulmonary resuscitation (CPR) outcomes in the dialysis population have largely been derived from claims data and are somewhat limited by a lack of detailed characterization of CPR events. We aimed to analyze CPR-related outcomes in individuals receiving maintenance dialysis. Retrospective chart review. Using electronic medical records from a single academic health care system, we identified all hospitalized adult patients receiving maintenance dialysis who had undergone in-hospital CPR between 2006 and 2014. Initial in-hospital CPR. Overall survival, predictors of unsuccessful CPR, predictors of death during the same hospitalization among initial survivors, predictors of discharge-to-home status. We provide descriptive statistics for the study variables and used t tests, χ2 tests, or Fisher exact tests to compare differences between the groups. We built multivariable logistic regression models to examine the CPR-related outcomes. A total of 184 patients received in-hospital CPR: 51 (28%) did not survive the initial CPR event, and 77 CPR survivors died (additional 42%) later during the same hospitalization (overall mortality 70%). Only 18 (10%) were discharged home, with the remaining 32 (17%) discharged to a rehabilitation facility or a nursing home. In the multivariable model, the only predictor of unsuccessful CPR was CPR duration (OR, 1.41; 95% CI, 1.24-1.61; P < 0.001). Predictors of death during the same hospitalization after surviving the initial CPR event were CPR duration (OR, 1.15; 95% CI 1.04-1.27; P = 0.007) and older age (OR, 1.64; 95% CI, 1.23-2.2; P < 0.001). Older people also had lower odds of discharge-to-home status (OR, 0.25; 95% CI, 0.11-0.54; P < 0.001). Retrospective study design, single-center study, no information on functional status. Patients receiving maintenance dialysis experience high mortality following in-hospital CPR and only 10% are discharged home. These data may help clinicians provide useful prognostic information while engaging in goals of care conversations.
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