EFFICIENT PERIPHERAL FUNCTIONALIZATION OF PORPHYRINS
EFFICIENT PERIPHERAL FUNCTIONALIZATION OF PORPHYRINS
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DOI：
10.1016/0040-4020(82)80211-1
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发表时间：
1982-01-01
期刊：
影响因子：
2.1
通讯作者：
DEBERNARDIS, J
中科院分区：
文献类型：
--
作者：
BALDWIN, JE;CROSSLEY, MJ;DEBERNARDIS, J
给出了由相应的卟啉温和而有效地合成β-取代的端基卟啉和中位-四苯基卟啉的细节。硝基衍生物被干净地还原为β-氨基卟啉，它容易被水解，但否则可以通过标准程序在氮气上进一步衍生化。在DMF[二甲基甲酰胺]中，β-硝基卟啉与硫酸盐离子反应得到β-烷基硫代卟啉、β-芳基硫代卟啉或相应的脱硝基卟啉，具体取决于硫醇。
Details are given for the mild and efficient synthesis of .beta.-substituted capped -porphyrins and meso-tetraphenylporphyrins from the corresponding porphyrins. The nitro derivatives are cleanly reduced to .beta.-aminoporphyrins, which are susceptible to hydrolysis but otherwise may be further derivatized on nitrogen by standard procedures. Treatment of .beta.-nitroporphyrins with thiolate ions in DMF [dimethylformamide] gave .beta.-alkylthioporphyrins, .beta.-arylthioporphyrins or the corresponding denitrated porphyrin, depending on the thiol.