Management of long-term catheter-related Brevibacterium bacteraemia
Management of long-term catheter-related Brevibacterium bacteraemia
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DOI：
10.1111/j.1469-0691.2004.00857.x
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发表时间：
2004-05-01
影响因子：
14.2
通讯作者：
Struelens, MJ
中科院分区：
文献类型：
--
作者：
Beukinga, I;Rodriguez-Villalobos, H;Struelens, MJ
据报道，短杆菌属是一种罕见的器械感染原因。在2例与手术植入血管内器械感染相关的复发性干酪短杆菌菌血症病例中，分别在通过感染导管完成万古霉素治疗后2个月和5个月复发。第二个静脉抗生素治疗过程中的抗生素锁定技术导致细菌学治愈的一名患者。分子分型结果表明，复发菌血症是由同一菌株引起的。除了适当的抗生素外，取出植入装置可能是必要的，以成功管理此类感染。
Brevibacterium has been reported as a rare cause of implanted-device infection. In two cases of recurrent Brevibacterium casei bacteraemia associated with infection of surgically implanted intravascular devices, relapse occurred 2 and 5 months, respectively, after completion of therapy with vancomycin via the infected catheter. A second intravenous antibiotic therapy course by the antibiotic-lock technique led to bacteriological cure in one patient. Molecular typing results demonstrated that the recurrent bacteraemia was caused by the same strain. Implanted-device removal may be necessary, in addition to appropriate antibiotics, for successful management of such infections.