Physical activity, including walking, and cognitive function in older women
Physical activity, including walking, and cognitive function in older women
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DOI：
10.1001/jama.292.12.1454
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发表时间：
2004-09-22
影响因子：
120.7
通讯作者：
Grodstein, F
中科院分区：
文献类型：
--
作者：
Weuve, J;Kang, JH;Grodstein, F
上下文体力活动可能有助于维持认知功能在老年adults.Objective要检查的关系，长期定期的体力活动，包括步行，认知功能，设计妇女报告参与闲暇时间的体力活动两年一次邮寄问卷调查开始于1986年。我们通过1986年问卷调查的平均能量消耗来评估长期活动，通过参与者的基线认知评估（1995年至2001年）。我们使用线性回归来估计2年内不同体力活动和步行水平的基线认知表现和认知下降的校正平均差异。包括18766名年龄在70到81岁之间的美国妇女。主要结果测量两次大约间隔2年的有效的认知电话评估（1995年至2001年和1997年至2003年），包括一般认知、言语记忆、类别流畅性和注意力测试。结果较高水平的活动与较好的认知表现相关。在综合所有6项测试结果的总体得分上，能量消耗第二至第五个五分位数的女性的平均得分比最低五分位数的女性高出0.06、0.06、0.09和0.10标准单位（趋势P
Context Physical activity may help maintain cognitive function in older adults.Objective To examine the relation of long-term regular physical activity, including walking, to cognitive function,Design Women reported participation in leisure-time physical activities on biennial mailed questionnaires beginning in 1986. We assessed long-term activity by averaging energy expenditures from questionnaires in 1986 through participants' baseline cognitive assessments (1995 to 2001). We used linear regression to estimate adjusted mean differences in baseline cognitive performance and cognitive decline over 2 years, across levels of physical activity and walking.Setting and Participants Nurses' Health Study, including 18766 US women aged 70 to 81 years.Main Outcome Measure Validated telephone assessments of cognition administered twice approximately 2 years apart (1995 to 2001 and 1997 to 2003), including tests of general cognition, verbal memory, category fluency, and attention.Results Higher levels of activity were associated with better cognitive performance. On a global score combining results of all 6 tests, women in the second through fifth quintiles of energy expenditure scored an average of 0.06, 0.06, 0.09, and 0.10 Standard units higher than women in the lowest quintile (P for trend