THICKENED CORTICAL BONES IN CONGENITAL NEUTROPENIA
THICKENED CORTICAL BONES IN CONGENITAL NEUTROPENIA
复制标题
DOI：
10.1007/bf02388088
复制
发表时间：
1987-02-01
影响因子：
2.3
通讯作者：
OLAUGHLIN, BJ
中科院分区：
文献类型：
--
作者：
BOECHAT, MI;GORMLEY, LS;OLAUGHLIN, BJ
先天性中性粒细胞减少症是一种罕见的疾病，可能是家族性的，具有广泛的临床表现。描述了三个患有严重疾病的姐妹，她们遭受了导致死亡的反复感染。回顾他们的X光照片，发现存在皮质增厚的骨骼。虽然有几种不同的骨异常综合征与中性粒细胞减少症有关，但先天性中性粒细胞减少症儿童的放射学发现皮质增厚尚未见报道。
Congenital neutropenia is an uncommon entity which may be familial and has a wide spectrum of clinical expression. Three sisters with the severe form of the disease, that suffered from recurrent infections which lead to their demise, are described. Review of their radiographs revealed the presence of cortical thickening of the bones. Although several syndromes with different bone abnormalities have been reported associated with neutropenia, the radiographic finding of thickened cortex in children with congenital neutropenia has not been previously described.