Calcium Antagonists in Aneurysmal Subarachnoid Hemorrhage
Calcium Antagonists in Aneurysmal Subarachnoid Hemorrhage
复制标题
钙拮抗剂治疗动脉瘤性蛛网膜下腔出血
DOI:
10.1161/01.str.0000177502.96190.71
复制
发表时间:
2005
期刊:
影响因子:
8.3
通讯作者:
J. Gijn
中科院分区:
文献类型:
--
作者:
G. Rinkel;Valery L. Feigin;A. Algra;W. Bergh;M. Vermeulen;J. Gijn
Section Editors: Geoffrey A. Donnan MD, FRACP Stephen M. Davis MD, FRACP
Secondary ischemia is a frequent cause of poor outcome in patients with subarachnoid hemorrhage (SAH). The cause of secondary ischemia is unknown, but may be related to vasospasm, at least in part. In experimental studies calcium antagonists prevent or reverse vasospasm and have neuroprotective properties. Various types of calcium antagonists have been studied in several clinical trials.
To determine the effectiveness of calcium antagonists for improving outcome in patients with aneurysmal SAH.
### Search Strategy
We searched the Cochrane Stroke Group Trials Register (September 2003). In addition, we searched MEDLINE (1966 to October 2003) and EMBASE (1980 to October 2003), hand-searched two Russian journals (1990 to 2003), and contacted trialists …