Calcium Antagonists in Aneurysmal Subarachnoid Hemorrhage

Calcium Antagonists in Aneurysmal Subarachnoid Hemorrhage
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钙拮抗剂治疗动脉瘤性蛛网膜下腔出血

DOI:
10.1161/01.str.0000177502.96190.71
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发表时间:
2005
期刊:
影响因子:
8.3
通讯作者:
J. Gijn
J. Gijn
中科院分区:
医学1区
文献类型:
--
作者:
G. Rinkel;Valery L. Feigin;A. Algra;W. Bergh;M. Vermeulen;J. Gijn

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栏目编辑:Geoffrey A.Donnan MD,FRACP Stephen M.Davis MD,FRACP 继发性脑缺血是蛛网膜下腔出血(SAH)患者预后不良的常见原因。继发性缺血的原因尚不清楚,但可能与血管痉挛有关,至少部分有关。在实验研究中,钙拮抗剂预防或逆转血管痉挛,并具有神经保护特性。各种类型的钙拮抗剂已经在几个临床试验中进行了研究。 目的:探讨钙拮抗剂对改善动脉瘤性蛛网膜下腔出血患者预后的效果。 #搜索策略 我们检索Cochrane卒中组试验登记(2003年9月)。此外,我们还检索了MEDLINE(1966-2003年10月)和EMBASE(1980年-2003年10月),手工检索了两种俄罗斯期刊(1990年-2003年),并联系了试验者…
Section Editors: Geoffrey A. Donnan MD, FRACP Stephen M. Davis MD, FRACP Secondary ischemia is a frequent cause of poor outcome in patients with subarachnoid hemorrhage (SAH). The cause of secondary ischemia is unknown, but may be related to vasospasm, at least in part. In experimental studies calcium antagonists prevent or reverse vasospasm and have neuroprotective properties. Various types of calcium antagonists have been studied in several clinical trials. To determine the effectiveness of calcium antagonists for improving outcome in patients with aneurysmal SAH. ### Search Strategy We searched the Cochrane Stroke Group Trials Register (September 2003). In addition, we searched MEDLINE (1966 to October 2003) and EMBASE (1980 to October 2003), hand-searched two Russian journals (1990 to 2003), and contacted trialists …