Clinical application of infrared thoracoscopy to detect bullous or emphysematous lesions of the lung
Clinical application of infrared thoracoscopy to detect bullous or emphysematous lesions of the lung
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DOI：
10.1016/j.jtcvs.2007.07.051
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发表时间：
2007-12-01
影响因子：
6
通讯作者：
Yokomise, Hiroyasu
中科院分区：
文献类型：
--
作者：
Gotoh, Masashi;Yamamoto, Yasumichi;Yokomise, Hiroyasu
目的：我们以前曾报道，红外胸腔镜是有用的，在检测肺气肿犬模型肺气肿病变。方法：应用红外线胸腔镜技术对8例自发性气胸患者进行有计划的肺大疱切除术。未观察到手术相关并发症。在手术干预期间，使用单次注射吲哚菁绿色（3.0 mg/kg）的红外线胸腔镜检查检测肺大疱性病变。根据红外线胸腔镜获得的彩色密度数据进行图像分析后，进行肺大疱性病变的部分切除术。结果：红外线胸腔镜下，肺大疱性或肺气肿性病变显示为白色，而正常肺组织显示为蓝色。我们能够发现小的大疱性病变与红外线胸腔镜，因为它更清晰的可视化相比，胸腔镜。定量彩色密度分析显示吲哚菁绿色强度明显降低，反映了大疱性病变血流减少。所有切除标本均经显微镜检查证实为肺大疱性病变。结论：红外线胸腔镜引导下肺切除术是一种安全有效的方法。
Objective: We have previously reported that infrared thoracoscopy was useful in detecting emphysematous lesions in a canine model of lung emphysema. We applied infrared thoracoscopy to determine the feasibility and efficacy of planning bullectomy for patients with spontaneous pneumothorax.Methods: A total of 8 patients with spontaneous pneumothorax were included in the study. No procedure-related complications were observed. Infrared thoracoscopy with a single injection of indocyanine green (3.0 mg/kg) was used to detect bullous lesions of the lung, during surgical intervention. Partial lung resections of the bullous lesions were performed after image analysis based on color density data obtained by means of infrared thoracoscopy.Results: Bullous or emphysematous lesions of the lung were demonstrated in white, whereas normal lung tissue was imaged in blue, under infrared thoracoscopy. We were able to detect small bullous lesions with infrared thoracoscopy because of its clearer visualization compared with thoracoscopy. Quantitative color-density analysis revealed a marked decrease of indocyanine green intensity, which reflected decreased blood flow of bullous lesions. All resected specimens were confirmed as bullous lesions based on microscopic examinations.Conclusion: Infrared thoracoscopy-guided lung resection is a safe and useful procedure in detecting small bullous lesions.