Rex Retroelements and Teleost Genomes: An Overview.

Rex Retroelements and Teleost Genomes: An Overview.
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DOI:
10.3390/ijms19113653
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发表时间:
2018-11-20
影响因子:
5.6
通讯作者:
Biscotti MA
Biscotti MA
中科院分区:
生物学2区
文献类型:
--
作者:
Carducci F;Barucca M;Canapa A;Biscotti MA

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重复DNA是基因组中尚未完全发现的有趣部分,并且在序列、基因组组织和进化模式方面显示出高度可变性。在基因组组织的基础上,它包括卫星DNA和转座因子,卫星DNA被组织为首尾相连的重复序列的长阵列,转座因子分散在整个基因组中。这些重复的元件代表了脊椎动物基因组中相当大的一部分,在物种进化中起着重要作用。在这篇综述中,我们将重点放在我们的注意力Rex1,Rex3和Rex6,三个元素的具体硬骨鱼基因组。我们报告的概述,这些retroelements突出其显着的影响,在染色质和异染色质组织,性染色体的分化,在形成额外的染色体,并在核型进化的硬骨鱼类的数据。
Repetitive DNA is an intriguing portion of the genome still not completely discovered and shows a high variability in terms of sequence, genomic organization, and evolutionary mode. On the basis of the genomic organization, it includes satellite DNAs, which are organized as long arrays of head-to-tail linked repeats, and transposable elements, which are dispersed throughout the genome. These repeated elements represent a considerable fraction of vertebrate genomes contributing significantly in species evolution. In this review, we focus our attention on Rex1, Rex3 and Rex6, three elements specific of teleost genomes. We report an overview of data available on these retroelements highlighting their significative impact in chromatin and heterochromatin organization, in the differentiation of sex chromosomes, in the formation of supernumerary chromosomes, and in karyotype evolution in teleosts.
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