A biopsychosocial model of pain and depression in rheumatoid arthritis: a 12-month longitudinal study

A biopsychosocial model of pain and depression in rheumatoid arthritis: a 12-month longitudinal study
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DOI:
10.1093/rheumatology/keg369
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发表时间:
2003-11-01
期刊:
影响因子:
5.5
通讯作者:
Howe, G
Howe, G
中科院分区:
医学1区
文献类型:
--
作者:
Covic, T;Adamson, B;Howe, G

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Objective.交叉验证一个生物心理社会模型,该模型使用身体残疾、无助感和被动应对来预测类风湿关节炎(RA)患者的抑郁和疼痛。在12个月的时间内,在三个时间点收集了157例RA患者的临床和心理测量结果。路径分析用于抑郁和疼痛的横向和纵向预测。无助感和被动应对被认为是身体残疾和未来抑郁和疼痛之间的关系的显着介质。在横截面上,预测模型可以解释52-94%的疼痛方差和37-71%的抑郁方差。纵向上,预测模型可以解释29-43%的疼痛方差和21-33%的抑郁方差。这些结果表明,身体残疾,无助和被动应对有显着的影响程度的疼痛和抑郁症患者经历的RA。
Objective. To cross-validate a biopsychosocial model using physical disability, helplessness and passive coping to predict depression and pain in rheumatoid arthritis (RA).Methods. Clinical and psychological measures were collected from 157 RA patients at three time points over a period of 12 months. Path analysis was used for cross-sectional and longitudinal prediction of depression and pain.Results. Helplessness and passive coping were found to be significant mediators of the relationship between the physical disability and future depression and pain. Cross-sectionally, the predictive model could account for 52-94% of the variance of pain and 37-71% of the variance of depression. Longitudinally, the predictive model could explain 29-43% of the variance of pain and 21-33% of the variance of depression.Conclusions. These results suggest that physical disability, helplessness and passive coping have a significant impact on the levels of pain and depression experienced by RA patients.