Symptom Experience in HIV-Infected Adults: A Function of Demographic and Clinical Characteristics
Symptom Experience in HIV-Infected Adults: A Function of Demographic and Clinical Characteristics
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DOI：
10.1016/j.jpainsymman.2009.05.013
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发表时间：
2009-12-01
影响因子：
4.7
通讯作者：
Aouizerat, Bradley E.
中科院分区：
文献类型：
--
作者：
Lee, Kathryn A.;Gay, Caryl;Aouizerat, Bradley E.
与艾滋病毒诊断及其医疗管理相互作用的个人特征会影响症状体验。人们对慢性病患者的症状如何随年龄、性别或社会经济因素的变化知之甚少。作为正在进行的前瞻性纵向研究的一部分，本报告描述了317名艾滋病毒/艾滋病患者的症状。参与者是在旧金山湾区的艾滋病毒诊所和社区网站招募的。测量方法包括来自医疗记录的最新CD4细胞计数和病毒载量、人口统计学和治疗变量，以及32项纪念症状评估量表，以评估每种症状的患病率、严重性和痛苦以及全球症状负担。症状的中位数是9个，超过一半的样本人口经历的症状包括精力不足(65%)、嗜睡(57%)、睡眠困难(56%)和疼痛(55%)。整体症状负担与年龄或CD4细胞计数无关。那些被诊断为艾滋病的人的症状负担得分明显更高，那些正在接受抗逆转录病毒治疗的人也是如此。非洲裔美国人报告的症状比高加索人或混合/其他种族少，而女性在控制艾滋病诊断和种族后报告更多的症状负担。由于高症状负担更有可能催生可能无效的自我护理策略，因此，来自医疗保健提供者的量身定制的干预措施将更好地指导症状管理策略。J疼痛症状管理2009；38：882-893。(C)2009年美国癌症疼痛缓解委员会。爱思唯尔公司出版，版权所有。
Personal characteristics that interact with both HIV diagnosis and its medical management can influence symptom experience. Little is known about how symptoms in populations with chronic illness vary by age, sex, or socioeconomic factors. As part of an ongoing prospective longitudinal study, this report describes symptoms experienced by 317 men and women living with HIV/AIDS. Participants were recruited at HIV clinics and community sites in, the San Francisco Bay Area. Measures included the most recent CD4 cell count and viral load from the medical record, demographic and treatment variables, and the 32-item Memorial Symptom Assessment Scale to estimate prevalence, severity, and distress of each symptom and global symptom burden. The median number of symptoms was nine, and symptoms experienced by more than half the sample population included lack of energy (65%), drowsiness (57%), difficulty sleeping (56%), and pain (55 %). Global symptom burden was unrelated to age or CD4 cell count. Those with an AIDS diagnosis had significantly higher symptom burden scores, as did those currently receiving antiretroviral therapy. African Americans reported fewer symptoms than Caucasians or Mixed/Other race, and women reported more symptom burden after controlling for AIDS diagnosis and race. Because high symptom burden is more likely to precipitate self-care strategies that may potentially be ineffective, strategies for symptom management would be better guided by tailored interventions from health care providers. J Pain Symptom Manage 2009;38:882-893. (C) 2009 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.