Functional anatomy of biological motion perception in posterior temporal cortex: An fMRI study of eye, mouth and hand movements
Functional anatomy of biological motion perception in posterior temporal cortex: An fMRI study of eye, mouth and hand movements
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DOI：
10.1093/cercor/bhi064
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发表时间：
2005-12-01
期刊：
影响因子：
3.7
通讯作者：
McCarthy, G
中科院分区：
文献类型：
--
作者：
Pelphrey, KA;Morris, JP;McCarthy, G
被动观看生物运动涉及人类颞枕后皮层的广泛区域，特别是颞上沟（STS）内部和附近。相对而言，我们对这一区域的功能特异性知之甚少。最近的一些研究强调了运动的感知意向性作为一种潜在的组织原则，而另一些研究则认为存在一种基于运动中感知到的肢体的躯体解剖。在这里，我们进行了一个与事件相关的功能性磁共振成像实验，以比较眼睛、嘴和手的运动所引起的活动。每一个动作都诱发了右侧后颞枕皮质的强烈激活。虽然该区域的激活图有大量重叠，但血流动力学反应幅度的空间分布区分了运动。口部运动引起STS后部中部的活动，而眼球运动引起右侧STS后部上部和后部的活动。手的运动激活了更多的STS区域的下和后部分，在STS的后连续分支。手诱发的活动也延伸到颞下回、枕中回和舌回。这种地形可能在一定程度上反映了特定身体运动在不同功能活动中的作用。
Passive viewing of biological motion engages extensive regions of the posterior temporal-occipital cortex in humans, particularly within and nearby the superior temporal sulcus (STS). Relatively little is known about the functional specificity of this area. Some recent studies have emphasized the perceived intentionality of the motion as a potential organizing principle, while others have suggested the existence of a somatotopy based upon the limb perceived in motion. Here we conducted an event-related functional magnetic resonance imaging experiment to compare activity elicited by movement of the eyes, mouth or hand. Each motion evoked robust activation in the right posterior temporal-occipital cortex. While there was substantial overlap of the activation maps in this region, the spatial distribution of hemodynamic response amplitudes differentiated the movements. Mouth movements elicited activity along the mid-posterior STS while eye movements elicited activity in more superior and posterior portions of the right posterior STS region. Hand movements activated more inferior and posterior portions of the STS region within the posterior continuing branch of the STS. Hand-evoked activity also extended into the inferior temporal, middle occipital and lingual gyri. This topography may, in part, reflect the role of particular body motions in different functional activities.