Prolactin in CSF selectively increases dopamine turnover in the median eminence.
Prolactin in CSF selectively increases dopamine turnover in the median eminence.
复制标题
脑脊液中的催乳素选择性地增加正中隆起的多巴胺周转。
DOI：
10.1016/0024-3205(78)90551-9
复制
发表时间：
1978
期刊：
影响因子：
6.1
通讯作者：
K. E. Moore
中科院分区：
文献类型：
--
作者：
L. Annunziato;K. E. Moore
开始脑室内注射 0.2-2 μg 大鼠催乳素后，16 岁时，α-甲基酪氨酸诱导的多巴胺下降在大鼠中位隆起中增加，但在 2 小时后没有增加。脑室内注射催乳素并不能改变α-甲基酪氨酸诱导的纹状体或嗅结节中多巴胺的下降。这些结果表明脑脊液中的催乳素可以选择性地增加结节漏斗部多巴胺能神经元的活性。
The α-methyltyrosine-induced decline of dopamine was increased in the median eminence of rats at 16 but not at 2 hours after the start of intraventricular injections of 0.2–2 μg of rat prolactin. Intraventricular injections of prolactin did not alter the α-methyltyrosine-induced decline of dopamine in the striatum or olfactory tubercle. These results suggest that prolactin in the cerebrospinal fluid can selectively increase the activity of tuberoinfundibular dopaminergic neurons.