Segmental arterial mediolysis of varying phases affecting both the intra-abdominal and intracranial vertebral arteries: an autopsy case report

Segmental arterial mediolysis of varying phases affecting both the intra-abdominal and intracranial vertebral arteries: an autopsy case report
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DOI:
10.1016/j.carpath.2009.02.002
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发表时间:
2010-07-01
影响因子:
3.7
通讯作者:
Fukunaga, Tatsushige
Fukunaga, Tatsushige
中科院分区:
医学4区
文献类型:
--
作者:
Ro, Ayako;Kageyama, Norimasa;Fukunaga, Tatsushige

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我们报告一例发生在颅内椎动脉(IVA)和腹腔内动脉的不同阶段的节段性动脉中膜溶解(SAM)的尸检病例。患者是一名70岁的男性,被发现死于家中。死亡原因是右胃大网膜动脉破裂引起的腹内大出血。组织病理学检查显示,SAM损伤期右胃大网膜动脉出现长达20 cm的宽动脉夹层。此外,胃左动脉在修复期观察到有组织的动脉夹层。此外,在修复阶段,SAM被检测为右侧IVA正在组织过程中的动脉夹层。这三个病变被认为是在不同的时间发生的。同时发生于腹内和颅内椎动脉的SAM极为罕见。这一巧合可能为SAM与自发性IVA夹层之间的关系提供线索。(C) 2010爱思唯尔公司版权所有。
We report an autopsy case of segmental arterial mediolysis (SAM) of various phases occurring in both the intracranial vertebral artery (IVA) and intra-abdominal arteries. The patient was a 70-year-old male found dead in his house. The cause of death was massive intra-abdominal hemorrhage owing to a ruptured right gastroepiploic artery. Histopathological examination revealed that there was a broad arterial dissection as long as 20 cm in the right gastroepiploic artery associated with SAM in the injurious phase. In addition, SAM in the reparative phase was observed as organized arterial dissections in the left gastric artery. Furthermore, SAM in the reparative phase was detected as an arterial dissection in the right IVA undergoing an organizing process. These three lesions were considered to have developed at different times. SAM occurring in both the intra-abdominal and intracranial vertebral arteries is extremely rare. This coincidence may provide a clue to the relationship between SAM and spontaneous IVA dissection. (C) 2010 Elsevier Inc. All rights reserved.