All-cause mortality in the Canterbury (New Zealand) insulin-treated diabetic registry population
All-cause mortality in the Canterbury (New Zealand) insulin-treated diabetic registry population
复制标题
DOI：
10.2337/diacare.24.1.56
复制
发表时间：
2001-01-01
期刊：
影响因子：
16.2
通讯作者：
Moir, CL
中科院分区：
文献类型：
--
作者：
Brown, LJ;Scott, RS;Moir, CL
目的-建立全因死亡率和预期寿命和死亡率的危险因素，在胰岛素治疗的糖尿病患者生活在坎特伯雷，新西兰。研究设计和方法-胰岛素治疗的糖尿病患者（n = 1,008）的坎特伯雷糖尿病登记处跟踪超过9年，他们的生命状态进行了测定。使用直接和间接方法对死亡率进行标准化。考克斯比例风险回归用于模拟人口统计学和临床协变量对生存时间的影响。结果-进入研究时，年龄范围为2.9 - 92.7岁，平均48.7 ± 20.4岁;糖尿病病程为0.1-58.5年，平均14.0 +/- 10.6年。在7，372人-年的随访中，有303例死亡，标准化死亡率比（SMR）为2.6（95% CI 2.4-3.0）。30-39岁人群的相对死亡率最高（SMR 9.2 [4.8-16.2]）。根据Segi世界标准人群标准化的糖尿病队列死亡率为16.2/1000。达到年龄，性别和临床亚型是死亡率的重要预测因素。1型糖尿病受试者的SMR和发病年龄
OBJECTIVE - To establish all-cause death rates and life expectancies of and risk factors for mortality in insulin-treated diabetic individuals living in Canterbury, New Zealand.RESEARCH DESIGN AND METHODS - Insulin-treated diabetic subjects (n = 1,008) on the Canterbury Diabetes Registry were tracked over 9 years, and their vital status was determined. Death rates were standardized using direct and indirect methods. Cox proportional hazard regression was used to model the effects of demographic and clinical covariates on survival time.RESULTS - At study entry, age ranged from 2.9 to 92.7 years, with mean 48.7 +/- 20.4 years; age at diagnosis was 0.2-88.9 years, mean 34.5 +/- 20.0 years; and duration of diabetes was 0.1-58.5 years, mean 14.0 +/- 10.6 years. There were 303 deaths in 7,372 person-years of follow-up with a standardized mortality ratio (SMR) of 2.6 (95% CI 2.4-3.0). Relative mortality was greatest for those aged 30-39 years (SMR 9.2 [4.8-16.2]). The death rate for the diabetic cohort standardized against the Segi world standard population was 16.2 per 1,000. Attained age, sex, and clinical subtype were significant predictors of mortality. The SMR for subjects with type 1 diabetes and age at onset