Ultra-high Resolution SPECT with CdTe Detectors
Ultra-high Resolution SPECT with CdTe Detectors
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DOI：
10.1007/978-3-540-89208-3_199
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Naoka Ohmura;K. Ogawa
中科院分区：
文献类型：
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作者：
Naoka Ohmura;K. Ogawa
在室温下工作的诸如CdTe和CdZnTe的半导体探测器促进了超高分辨率SPECT系统的实现。这些半导体探测器用作像素化探测器，因此固有分辨率可以等于用于测量的像素的大小。采用最先进的半导体技术，探测器像素的尺寸可以小到0.5 × 0.5 mm 2，因此在临床研究中，使用超高分辨率平行孔准直器重建的SPECT图像的空间分辨率可以小于1 - 2 mm FWHM。如果我们将这种探测器应用于针孔SPECT系统，我们可以在小动物研究中获得超高分辨率的SPECT图像。为了阐明超高分辨率SPECT系统的可行性，我们用市售的半导体探测器进行了实验。实验中使用的像素尺寸为0.5 × 0.5 mm 2。在这个真实的SPECT系统中，我们新开发了一种超高分辨率的平行孔准直器和针孔准直器，它们都是由钨制成的。平行孔准直器和针孔准直器的实验结果表明，我们的SPECT系统可以分辨1.0 mm的热棒和1.6 mm的冷棒。
Semiconductor detectors such as CdTe and CdZnTe that work at room temperature have facilitated the realization of an ultra-high resolution SPECT system. These semiconductor detectors are used as pixellated detectors, and so the intrinsic resolution can be equal to the size of the pixel used for measurement. The size of the detector pixel can be as small as 0.5 × 0.5 mm2with state-of-the-art semiconductor technology, so that the spatial resolution of a reconstructed SPECT image with an ultra-high resolution parallel-hole collimator may be less than 1 – 2 mm FWHM in clinical studies. And if we apply this detector to a pinhole SPECT system, we can obtain ultra-high resolution SPECT images in small animal studies. To clarify the feasibility of an ultra-high resolution SPECT system, we conducted experiments with a commercially available semiconductor detector. The size of the pixel used in the experiments was 0.5 × 0.5 mm2. In this real SPECT system we newly developed an ultra-high resolution parallel-hole collimator and pinhole collimator that were made of tungsten. The results of the experiments with the parallel-hole collimator and pinhole collimator showed that our SPECT system could resolve 1.0 mm hot-rods and 1.6 mm cold rods.