[Use of combined treatment of rectal cancer involving metastases to regional lymph nodes].
[Use of combined treatment of rectal cancer involving metastases to regional lymph nodes].
复制标题
联合治疗直肠癌区域淋巴结转移的应用[J].
DOI：
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发表时间：
2006
期刊：
影响因子：
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通讯作者：
S. Iskhagi
中科院分区：
文献类型：
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作者：
I. A. Barsukov;O. Vlasov;S. I. Tkachëv;A. Nikolaev;R. Tamrazov;A. Malikhov;S. Iskhagi
与术前单纯放疗相比，术前和术中联合放疗直肠癌区域淋巴结转移未能降低局部复发率或改善5年疗效。此外，远处转移率仍然相当高（约30%）。然而，术前放疗加局部SHF热疗后，局部区域复发率显着下降（至2.3%），与单独手术和联合治疗，术前超分割放疗（TTD 25戈伊）。远处转移率降至25%。此外，5年生存率显著增加。
Use of combined pre- and intraoperative radiotherapy for rectal cancer involving metastases to regional lymph nodes failed to lower incidence of loco-regional recurrences or improve 5-year results, as compared with pre-operative radiotherapy alone. Besides, distant metastasis rates remained rather high (ca.30%). However, pre-operative radiotherapy plus local SHF-hyperthermia were followed by a significant drop in loco-regional recurrence incidence (to 2.3%), as compared with surgery alone and combined treatment using pre-operative hyper-fractionated-radiotherapy (TTD 25 Gy). Distant metastasis rates dropped to 25%. Also, 5-year survival increased significantly.