Gender differences in health-related quality of life at the time of a positive HIV test - a cross-sectional study in a resource-poor, high prevalence setting in Nairobi, Kenya.
Gender differences in health-related quality of life at the time of a positive HIV test - a cross-sectional study in a resource-poor, high prevalence setting in Nairobi, Kenya.
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HIV 检测呈阳性时健康相关生活质量的性别差异 - 在肯尼亚内罗毕资源匮乏、患病率高的环境中进行的一项横断面研究。
DOI：
10.1080/09540121.2017.1417970
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发表时间：
2018
期刊：
影响因子：
1.7
通讯作者：
Lester,RichardT
中科院分区：
文献类型：
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作者：
vanderKop,MiaL;Muhula,Samuel;Patel,Anik;Thabane,Lehana;Awiti,Patricia;Kyomuhangi,Lennie;Abunah,Bonface;Nagide,PatrickI;Smillie,Kirsten;Ojakaa,DavidI;Kimani,Joshua;Ekström,AnnaMia;Lester,RichardT
很少有研究审查撒哈拉以南非洲的性别差异，那里的艾滋病毒对妇女的影响不成比例。这项横断面研究的目的是确定在阳性HIV检测时HRQoL的性别差异，以及与HRQoL相关的因素是否在男性和女性之间存在差异。艾滋病毒检测呈阳性的成年人是从位于非正规住区的两个诊所招募的。使用SF-12测量HRQoL。多元线性回归用于检验身体（PCS）和心理综合评分（MCS）是否存在性别差异。为男性和女性建立了单独的模型，以检查与HRQoL相关的因素。在2013年4月至2015年6月期间，招募了775人。女性的平均PCS评分较高（校正后的平均差异为2.49，95%CI为0.54 - 4.44，p = 0.012）。MCS评分无显著性别差异。类似的因素与男性和女性更好的身体HRQoL相关：中学教育，年龄较小，较高的CD 4和就业。就业是与男性MCS相关的唯一因素，而较少的社会支持和低CD 4与女性MCS评分较差相关。在更广泛的政策和干预措施中，应考虑与HRQoL相关因素的性别差异，以改善诊断为艾滋病毒感染者的HRQoL。
Few studies have examined gender differences in sub-Saharan Africa, where HIV disproportionately affects women. Objectives of this cross-sectional study were to determine gender differences in HRQoL at the time of a positive HIV test, and whether factors associated with HRQoL differed between men and women. Adults testing HIV-positive were recruited from two clinics located in informal settlements. HRQoL was measured with the SF-12. Multiple linear regression was used to test whether there were gender differences in physical (PCS) and mental composite summary (MCS) scores. Separate models were built for men and women to examine factors associated with HRQoL. Between April 2013 and June 2015, 775 individuals from were recruited. The mean PCS score was higher in women (adjusted mean difference 2.49, 95% CI 0.54 to 4.44,p= 0.012). There was no significant gender difference in MCS scores. Similar factors were associated with better physical HRQoL in men and women: secondary education, younger age, higher CD4, and employment. Employment was the only factor associated with MCS in men, while less social support and low CD4 were associated with poorer MCS scores in women. Gender differences in factors related to HRQoL should be considered in broader policy and interventions to improve the HRQoL in those diagnosed with HIV.