Computerized measurement of cognitive impairment and associated neuropsychiatric dimensions
Computerized measurement of cognitive impairment and associated neuropsychiatric dimensions
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DOI：
10.1053/comp.2000.9015
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发表时间：
2000-09-01
影响因子：
7.3
通讯作者：
Carcamo, D
中科院分区：
文献类型：
--
作者：
Gottschalk, LA;Bechtel, RJ;Carcamo, D
本研究旨在交叉验证计算机软件程序检测和测量的能力，采用一种测量方法，应用于药物滥用患者5分钟语音样本的内容和形式分析，认知障碍和相关的共病神经精神心理生物学维度。在加州大学欧文分校（UCI）神经精神病学中心，对28名使用非法药物的住院吸毒患者进行了临床评估。通过计算机化内容分析方法得出的他们的认知障碍得分与Halstead-Reitan神经心理测试单元、计算机化自动神经心理评估度量单元（ANAM）、阿尔茨海默病评估量表-认知部分、Stroop颜色和单词测试、符号数字模式测试和控制口头单词联想测试等选定测试的得分进行比较。这些不同测量的得分与计算机化内容分析测量的得分相关性的统计显著性（p值）小于。0.05 ~ 0.001。对这些滥用药物的患者进行的每项测量中，计算机内容分析测量和一些ANAM神经心理学测量的比较“命中率”为75%至89%，而对其他神经心理学测量的比较“命中率”为25%至64%。总之，应用于5分钟言语样本的计算机化内容分析方法是一种有效、快速、易于管理的测量工具，用于评估认知障碍的程度和共病的神经精神维度。版权所有(C) 2000由W.B. Saunders公司。
This study aimed to cross-validate the capacity of a computer software program to detect and measure, using a measurement method applied to the content and form analysis of 5-minute speech samples, cognitive impairment and associated comorbid neuropsychiatric psychobiological dimensions in drug-abusing patients. At the University of California-Irvine (UCI) Neuropsychiatric Center, 28 drug-abusing inpatients using illegal drugs were clinically evaluated. Their scores for cognitive impairment derived by the computerized content analysis method were compared with scores derived from selected tests from the Halstead-Reitan Neuropsychological Test Battery, the computerized Automated Neuropsychological Assessment Metric Battery (ANAM), the Alzheimer's Disease Assessment Scale-Cognitive Portion, the Stroop Color and Word Test, the Symbol Digit Modalities Test, and the Controlled Oral Word Association Test. The statistical significance (Pvalue) of the correlations of scores from these different measures with scores obtained from the computerized content analysis measures was less than .05 to .001. The comparative "hit rate," detecting cognitive impairment above the norms for each measure administered to these drug-abusing patients, for the computerized content analysis measures and some of the ANAM neuropsychological measures was 75% to 89%, and for the other neuropsychological measures, 25% to 64%. In conclusion, the computerized content analysis methodology applied to 5-minute verbal samples is a valid, rapid, easily administered measurement instrument for assessing the magnitude of cognitive impairment and comorbid neuropsychiatric dimensions. Copyright (C) 2000 by W.B. Saunders Company.