Effects of polyphenol-rich chokeberry juice on cellular antioxidant enzymes and membrane lipid status in healthy women
Effects of polyphenol-rich chokeberry juice on cellular antioxidant enzymes and membrane lipid status in healthy women
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DOI：
10.1016/j.jff.2014.04.019
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发表时间：
2014-07-01
影响因子：
5.6
通讯作者：
Konic-Ristic, Aleksandra
中科院分区：
文献类型：
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作者：
Kardum, Nevena;Takic, Marija;Konic-Ristic, Aleksandra
研究了25名健康女性长期饮用富含多酚的酸梅汁对红细胞抗氧化酶活性和膜脂状态的影响。在基线、中间和3个月的消费期结束时，评估膜脂肪酸、超氧化物歧化酶（SOD）和谷胱甘肽过氧化物酶（GPx）活性的变化。结果表明，在实验结束时，C22：6 n-3、n-3多不饱和脂肪酸（PUFAs）、总PUFAs和不饱和指数显著升高，单不饱和脂肪酸（MUFAs）和n-6：n-3比值显著降低，SOD和GP（x）活性显著升高。在食用期间，血脂和血糖稳定，而硫代巴比妥酸反应物质（TBARS）水平，作为血清脂质过氧化反应的指标，显着降低。这些结果表明，定期chokeberry果汁消费对细胞氧化损伤的积极影响，并建议其在保护氧化应激的假定作用。(C)2014爱思唯尔有限公司版权所有。
The effect of long-term polyphenol-rich chokeberry juice consumption on activities of antioxidant enzymes and membrane lipid status in erythrocytes of 25 healthy women was examined. Percentages of membrane fatty acids, superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities were assessed at a baseline, in the middle and at the end of a 3-month-long consumption period. A significant increase in C22:6n-3, n-3 polyunsaturated fatty acids (PUFAs), total PUFAs and unsaturation index and a significant decrease in monounsaturated fatty acids (MUFAs) and n-6:n-3 ratio were found. Significantly higher SOD and GP(x) activities were also recorded at the end of the study. Serum lipids and glucose were stabile during the consumption period, while the levels of thiobarbituric acid-reactive substances (TBARS), as serum indicator of lipid peroxidation, were reduced significantly. These results indicate a positive impact of regular chokeberry juice consumption on cellular oxidative damage and suggest its putative role in the protection against oxidative stress. (C) 2014 Elsevier Ltd. All rights reserved.