Nature: A rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy
Nature: A rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy
复制标题
DOI：
10.1002/lsm.20352
复制
发表时间：
2006-06-01
影响因子：
2.4
通讯作者：
Dougherty, Thomas J.
中科院分区：
文献类型：
--
作者：
Pandey, Ravindra K.;Goswami, Lalit N.;Dougherty, Thomas J.
The purpose of this review is to call attention in the use of chlorophyll-a and bacteriochlorophyll-a to develop more than 600 photosensitizers (lambda(max) 660 nm-800 nm) during the last 15 years (1990-2005) at the Photodynamic Therapy Center, Roswell Park Cancer Institute, Buffalo. This article mainly includes the chemistry, preclinical results, and brief clinical data of some of the most effective photosensitizers. The utility of the tumor-avid photosensitizers in developing multimodality agents (imaging and therapy) is also presented.
