INFANT SALT TASTE - DEVELOPMENTAL, METHODOLOGICAL, AND CONTEXTUAL FACTORS
INFANT SALT TASTE - DEVELOPMENTAL, METHODOLOGICAL, AND CONTEXTUAL FACTORS
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DOI：
10.1002/dev.420270604
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发表时间：
1994-09-01
影响因子：
2.2
通讯作者：
MARSH, RR
中科院分区：
文献类型：
--
作者：
BEAUCHAMP, GK;COWART, BJ;MARSH, RR
两项研究调查了人类婴儿在发育过程中对盐的反应。在第一项研究中，从两组婴儿（新生儿和4至8个月大的婴儿）中获得摄入量和吸吮量，以响应两种浓度的盐（0.2或0.4 M）和水的简短介绍。对于几个措施的吸吮和摄入量，有显着的年龄和浓度的影响。一般来说，新生儿倾向于拒绝盐水相对于水比4至8个月大的婴儿。这一结果与先前发表的研究一致，表明人类婴儿对盐的接受性和敏感性发生了发育变化。在第二项纵向研究中，每月对2至7个月大的婴儿对加盐（0.15 M）与无盐配方奶粉的反应进行评估。再一次观察到了发育变化：根据一些吸吮测量，相对于无盐配方奶粉，年龄较小的婴儿似乎对加盐配方奶粉漠不关心，而年龄较大的婴儿倾向于拒绝加盐配方奶粉，可能是因为它比无盐配方奶粉甜，或者因为它是新的。这些数据与动物模型研究的假设一致，即在人类出生后的早期发育过程中，对盐度敏感的转导元件成熟。(C)1991年John Wiley and Sons，Inc.
Two studies investigated the human infant's response to salt during development. In the first study, measures of intake and sucking were obtained from two groups of infants, newborns and 4- to 8-month-olds, in response to brief presentations of two concentrations of salt (0.2 or 0.4 M) and water. For several measures of sucking and for intake, there were significant age and concentration effects. Generally, newborn infants tended to reject saline relative to water more than did 4- to 8-month-old infants. This result, consistent with previously published research, suggests a developmental change in salt acceptability and, probably, sensitivity in the human infant. In the second longitudinal study, the response to salted (0.15 M) versus unsalted formulas was evaluated monthly in infants 2 to 7 months of age. Again, a developmental change was observed: Based on some sucking measures, younger infants appeared to be indifferent to the salted formula relative to the unsalted formula whereas older infants tended to reject the salted formula, presumably because either it was less sweet than the unsalted formulas or because it was novel. These data are consistent with the hypothesis developed from animal model studies that during early human postnatal development, transductive elements sensitive to saltiness mature. (C) 1991 John Wiley and Sons, Inc.