Transmission of the agent of human granulocytic ehrlichiosis by host-seeking Ixodus scapularis (Acari: Ixodidae) in southern New York state
Transmission of the agent of human granulocytic ehrlichiosis by host-seeking Ixodus scapularis (Acari: Ixodidae) in southern New York state
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DOI：
10.1093/jmedent/34.4.379
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发表时间：
1997-07-01
影响因子：
2.1
通讯作者：
Fish, D
中科院分区：
文献类型：
--
作者：
DesVignes, F;Fish, D
肩部硬蜱说，从纽约州韦斯特切斯特县人类粒细胞性埃立克体病(HGE)的自然疫源地收集的若虫，将HGE制剂传播给实验室中未感染的小鼠。8只小鼠中有3只通过全血聚合酶链式反应分析和血涂片显微镜检查桑囊虫而证实感染。其中两只小鼠的异种诊断也呈阳性。异种诊断阳性幼虫通过蜕皮维持感染，并将感染转移到3只小鼠中的1只。自然感染的肩隆伊蚊将人类粒细胞性埃立克体病的病原体传播给小鼠，但肩隆伊蚊对这种病原体的获取和传播似乎没有莱姆病的病原体伯氏疏螺旋体、施密德、海德、施泰格沃特和布伦纳预期的那么有效。
Ixodes scapularis Say nymphs collected from a natural focus of human granulocytic ehrlichiosis (HGE) in Westchester County, New York, transmitted the HGE agent to uninfected mice in the laboratory. Infection was demonstrated in 3 of 8 mice by polymerase chain reaction analysis of whole blood and microscopic examination of blood smears for morulae. Two of these mice were also positive by xenodiagnosis. Positive xenodiagnostic larvae maintained infection through molting and transferred infection to 1 of 3 mice. Naturally infected I. scapularis ticks transmit the agent of human granulocytic ehrlichiosis to mice, but both acquisition and transmission of this agent by I. scapularis appear to be less efficient than would be expected for Borrelia burgdoferi Johnson, Schmid, Hyde, Steigerwalt & Brenner, the agent of Lyme disease.