PREDICTION OF OUTCOME AFTER CARDIAC-ARREST
PREDICTION OF OUTCOME AFTER CARDIAC-ARREST
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DOI：
10.1097/00003246-198709000-00004
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发表时间：
1987-09-01
影响因子：
8.8
通讯作者：
RONQUIST, G
中科院分区：
文献类型：
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作者：
EDGREN, E;HEDSTRAND, U;RONQUIST, G
对32例心脏骤停后缺氧缺血性昏迷的神经系统预后进行了研究。缺血损伤后24和48 h分别进行观察和采集标本。评估格拉斯哥-匹兹堡昏迷评分的预后价值。研究的其他变量是脑电图和脑脊液（CSF）中的腺苷酸激酶、乳酸和谷胱甘肽。如果患者在6个月的随访期内恢复独立生活，则结果良好。预测和良好预后之间最密切的相关性出现在格拉斯哥-匹兹堡昏迷评分（94%）和48小时检查时的脑电图（77%），48小时时修改的昏迷评分（96%）和24小时时的CSF乳酸（78%）。在规定的时间点，一些简单的神经体征（例如，对疼痛没有戒断反应）与不良预后100%相关，尽管它们的缺失并不一定与良好预后相关。
Neurologic outcome of hypoxic ischemic coma after cardiac arrest was studied in 32 patients. Observations were made and samples collected 24 and 48 h after the ischemic insult. The Glasgow-Pittsburgh coma score was assessed for its prognostic value. Other variables studied were the EEG and adenylate kinase, lactate and glutathione in the cerebrospinal fluid (CSF). Outcome was termed good if the patients resumed an independent life within a 6-month follow-up period. The closest correlations between prediction and good outcome occurred with the Glasgow-Pittsburgh coma score (94%) and the EEG (77%) at the 48-h examination, a modified coma score (96%) at 48 h, and CSF lactate (78%) at 24 h. Some simple neurologic signs (eg, no withdrawal response to pain) at stated points in time was 100% associated with a bad outcome, although their absence was not associated necessarily with a good prognosis.