Sleep Disturbances and the Risk of Incident Suicidality: A Systematic Review and Meta-Analysis of Cohort Studies

Sleep Disturbances and the Risk of Incident Suicidality: A Systematic Review and Meta-Analysis of Cohort Studies
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DOI:
10.1097/psy.0000000000000964
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发表时间:
2021-09-01
影响因子:
3.3
通讯作者:
Xiang, Yu-Tao
Xiang, Yu-Tao
中科院分区:
医学3区
文献类型:
--
作者:
Dong, Min;Li Lu;Xiang, Yu-Tao

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目的:睡眠障碍与自杀之间的关系尚不清楚,部分原因是研究结果的可变性。本荟萃分析旨在探讨睡眠障碍对事件自杀的预测价值。方法:系统检索PubMed、EMBASE、PsycINFO和Web of Science数据库中有关睡眠障碍和事件自杀的研究。按照注册方案筛选队列研究,并对符合条件的研究进行荟萃分析。结果:纳入了7项研究,包括基线时的1,570,181人,随访期间有1407人企图自杀,1023人完成自杀。有基线睡眠障碍的个体的自杀率明显高于无基线睡眠障碍的个体(相对危险度= 2.17,95%可信区间[CI] = 1.45-3.24, I-2 = 82.50%, p
Objective: The association between sleep disturbances and suicidality is not well understood partly because of the variability in research results. This meta-analysis aimed to investigate the predictive value of sleep disturbances for incident suicidality.Methods: A systematic search was conducted in PubMed, EMBASE, PsycINFO, and Web of Science databases for studies examining sleep disturbances and incident suicidality. Cohort studies were screened following a registered protocol, and the eligible ones were meta-analyzed.Results: Seven studies comprising 1,570,181 individuals at baseline, with 1407 attempting suicide and 1023 completing suicide during follow-up, were included. Individuals with baseline sleep disturbances had a significantly higher incidence of suicidality than did those without (relative risk = 2.17, 95% confidence interval [CI] = 1.45-3.24, I-2 = 82.50%, p