The chemistry of caries: remineralization and demineralization events with direct clinical relevance.
The chemistry of caries: remineralization and demineralization events with direct clinical relevance.
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DOI：
10.1016/j.cden.2010.03.004
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发表时间：
2010-07-01
影响因子：
--
通讯作者：
Gonzalez-Cabezas, Carlos
中科院分区：
文献类型：
--
作者：
Gonzalez-Cabezas, Carlos
龋齿是一种部位特异性疾病，在病变发展过程中经历许多去矿化和再矿化循环。由于其发育特征的动力学，龋损可以被阻止，甚至修复在其早期阶段，而无需手术干预，通过增加净矿物质获得在脱矿和再矿化周期。这一结果可以通过减少致龋生物膜和饮食等病因因素的影响，以及增加唾液和氟化物等矿化剂的功效来实现。
Dental caries is a site-specific disease that undergoes many cycles of demineralization and remineralization during lesion development. Because of its developmental characteristics dynamics, the caries lesion can be arrested and even repaired at its early stages without operative intervention by increasing the net mineral gain during the demineralization and remineralization cycles. This result can be accomplished by reducing the effect of etiological factors such as cariogenic biofilms and diet, and increasing the efficacy of remineralizing agents such as saliva and fluoride.