Scaling of neuron number and volume of the pulvinar complex in new world primates: Comparisons with humans, other primates, and mammals
Scaling of neuron number and volume of the pulvinar complex in new world primates: Comparisons with humans, other primates, and mammals
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DOI：
10.1002/cne.21406
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发表时间：
2007-09-02
影响因子：
2.5
通讯作者：
Finlay, Barbara L.
中科院分区：
文献类型：
--
作者：
Chalfin, Brandon P.;Cheung, Desmond T.;Finlay, Barbara L.
外侧后核和枕（LP枕复合体）是灵长类顶叶皮质背侧流和腹侧流发育的主要丘脑核团。在人类中，已经观察到枕神经元亚群的一个新的起源部位，即端脑的神经节隆起。已经提出神经元起源的该额外位点有助于枕的进化扩展（Letinic和Rakic [20011 Nat Neurosci 4：930-936）。然而，与人类相比，对长臂猿、黑猩猩和大猩猩中的LP枕复合体中的神经元数量的研究并未表明人类LP枕出乎意料地大（Armstrong [198 11 Am J Phys Anthropol 55：369-383）。在这里，我们扩大了异速生长的基础上进行比较，确定神经元数量的LP枕复合体的6个新世界灵长类动物（Cebus apella，Saimiri ustius，Saguinus midas尼日尔，Alouatta caraya，Aotus azarae，Callicebus moloch），以及测量LP枕体积进一步设置的24个物种，包括其他灵长类动物，食肉动物和啮齿类动物。在所有检查的物种中，LP枕复合体的体积与脑体积呈正异速生长关系。在新大陆灵长类和类人猿中，LP枕复合体中神经元数量的比例非常相似，人类的LP枕值接近回归线。在较大样本中LP枕的相对体积的比较证实了这一观察结果，并进一步证明灵长类动物和食肉动物与啮齿动物相比，其大小显示出“等级转移”，枕占总脑体积的比例更大。昼夜，夜间，或黄昏生态位没有歧视LP枕大小类群。
The lateral posterior nucleus and pulvinar (LP-pulvinar complex) are the principal thalamic nuclei associated with the elaborate development of the dorsal and ventral streams of the parietal cortex in primates. In humans, a novel site of origin for a subpopulation of pulvinar neurons has been observed, the ganglionic eminence of the telencephalon. This additional site of neuron origin has been proposed to contribute to the pulvinar's evolutionary expansion (Letinic and Rakic [20011 Nat Neurosci 4:930-936). Studies of neuron number in the LP-pulvinar complex in gibbon, chimpanzee, and gorilla compared to humans, however, did not show that the human LP-pulvinar was unexpectedly large (Armstrong [198 11 Am J Phys Anthropol 55:369-383). Here we enlarge the allometric basis for comparison by determining neuron number in the LP-pulvinar complex of six New World primates (Cebus apella, Saimiri ustius, Saguinus midas niger, Alouatta caraya, Aotus azarae, and Callicebus moloch) as well as measuring LP-pulvinar volume in a further set of 24 species including additional primates, carnivores, and rodents. The volume of the LP-pulvinar complex scaled with positive allometry with respect to brain volume across all species examined. The scaling of the number of neurons in the LP-pulvinar complex was extremely similar in New World primates and anthropoid apes, with the human LP-pulvinar value close to the regression line. Comparison of the relative volumes of the LP-pulvinar in the larger sample confirmed this observation, and further demonstrated that both primates and carnivores showed a "grade shift" in its size compared to rodents, with the pulvinar comprising a greater proportion of total brain volume across the board. Diurnal, nocturnal, or crepuscular niche did not discriminate LP-pulvinar size across taxa.