Early life predictors of atrial fibrillation-related mortality: Evidence from the health and retirement study
Early life predictors of atrial fibrillation-related mortality: Evidence from the health and retirement study
复制标题
DOI：
10.1016/j.healthplace.2012.12.008
复制
发表时间：
2013-05-01
期刊：
影响因子：
4.8
通讯作者：
Patton, Kristen K.
中科院分区：
文献类型：
--
作者：
Glymour, M. Maria;Benjamin, Emelia J.;Patton, Kristen K.
先前的研究发现，出生在东南部6个州（aff危险区）的美国人与aff相关的死亡风险较高，但没有确定机制。我们假设af相关死亡率与af危险区出生之间的关联可以通过儿童社会劣势或成人危险因素指标来解释。在美国健康与退休研究的24,323名参与者中，我们发现出生在af危险区与af相关死亡率的危险显著相关。在白人中，这种关系只与出生地有关，而与成年后的居住地无关。父亲的教育程度和主观评估的儿童社会经济地位都不能预测af相关的死亡率。传统的儿童和成人心血管危险因素并不能解释出生地和房颤相关死亡率之间的联系。(C) 2013 Elsevier Ltd.版权所有。
Prior research found that Americans born in 6 southeastern states (the AF-risk zone) had elevated risk of AF-related mortality, but no mechanisms were identified. We hypothesized the association between AF-related mortality and AF-risk zone birth is explained by indicators of childhood social disadvantage or adult risk factors. In 24,323 participants in the US Health and Retirement Study, we found that birth in the AF-risk zone was significantly associated with hazard of AF-related mortality. Among whites, the relationship was specific to place of birth, rather than place of adult residence. Neither paternal education nor subjectively assessed childhood SES predicted AF-related mortality. Conventional childhood and adult cardiovascular risk factors did not explain the association between place of birth and AF-related mortality. (C) 2013 Elsevier Ltd. All rights reserved.