Complementary memory systems: competition, cooperation and compensation
Complementary memory systems: competition, cooperation and compensation
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DOI：
10.1016/j.tins.2005.02.004
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发表时间：
2005-04-01
影响因子：
15.9
通讯作者：
Burgess, N
中科院分区：
文献类型：
--
作者：
Hartley, T;Burgess, N
空间导航依赖于可分离的记忆系统，这些记忆系统具有不同的神经基础，并采用不同的表征形式。一个系统逐渐获得对给定情况的可靠反应序列（例如重复遵循固定路线），并依赖于纹状体。另一种发展出灵活的表征，允许新的反应（例如找到新的捷径），并依赖于海马体。Voermans及其同事在临床人群中使用功能性神经成像和行为测量来探索这两个系统之间的相互作用。
Spatial navigation depends on dissociable memory systems that have distinct neural bases and employ different forms of representation. One system gradually acquires reliable sequences of responses to given situations (e.g. repeatedly following a fixed route), and depends on the striatum. The other develops flexible representations permitting novel responses (e.g. finding new shortcuts), and depends on the hippocampus. Voermans and colleagues explore the interaction between these two systems using functional neuroimaging and behavioural measures in a clinical population.