A Review of Dietary Ziziphus jujuba Fruit (Jujube): Developing Health Food Supplements for Brain Protection.

A Review of Dietary Ziziphus jujuba Fruit (Jujube): Developing Health Food Supplements for Brain Protection.
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DOI:
10.1155/2017/3019568
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发表时间:
2017
期刊:
Evidence-based complementary and alternative medicine : eCAM
影响因子:
--
通讯作者:
Tsim KWK
Tsim KWK
中科院分区:
其他
文献类型:
--
作者:
Chen J;Liu X;Li Z;Qi A;Yao P;Zhou Z;Dong TTX;Tsim KWK

文献摘要

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枣的果实,被称为枣或中国枣,因其对健康的益处而在世界各地被消费,既作为食物又作为草药。传统上,枣的主要功能之一,正如草药中所描述的那样,是通过平静心灵和改善睡眠质量来有益于我们的大脑。本文就其在神经系统中的作用进行了综述和讨论。拟南芥具有神经保护活性,包括保护神经元细胞免受神经毒素应激,刺激神经元分化,增加神经营养因子的表达,以及促进记忆和学习。黄酮类、cAMP和甘草苷可能是引起上述生物活性的潜在活性成分。这些研究结果表明,枣是一个潜在的候选人,为预防和/或治疗神经系统疾病的保健品的发展。
The fruits of Ziziphus jujuba, known as jujube or Chinese date, are being consumed all around the world because of their health benefits, as both food and herbal medicine. Traditionally, one of the main functions of jujube, as described in herbal medicine, is to benefit our brain by calming down the mind and improving quality of sleep. Here, the activities of jujubes on nervous system are summarized and discussed. Jujube possesses neuroprotective activities, including protecting neuronal cells against neurotoxin stress, stimulating neuronal differentiation, increasing expression of neurotrophic factors, and promoting memory and learning. Flavonoid, cAMP, and jujuboside could be the potential bioactive ingredients to account for the aforesaid biological activities. These findings imply that jujube is a potential candidate for development of health supplements for prevention and/or treatment of neurological diseases.