Polyanhydrides: the effects of ring substitution changes on polymer properties
Polyanhydrides: the effects of ring substitution changes on polymer properties
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DOI：
10.1007/s002890050435
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发表时间：
1999-01-01
期刊：
影响因子：
3.2
通讯作者：
Uhrich, KE
中科院分区：
文献类型：
--
作者：
Campo, CJ;Anastasiou, T;Uhrich, KE
我们合成的聚合物克服了与芳香聚酸酐相关的加工问题。本文主要研究了邻位取代聚酸酐、聚[1,3-二（邻羧基苯氧基）丙烷酐]（o-CPP）和聚[1,6-二（邻羧基苯氧基）己烷酐]（p-CPH）的合成和表征。通过延长芳基之间的烷基链（从丙烷到己烷）和改变环取代模式从对-到邻-，我们观察到芳香聚酸酐的溶解性增强。最终，这些聚酸酐可以用作聚合物支架，用作功能性软组织替代品。
We synthesized polymers that overcome the processing problems associated with aromatic polyanhydrides. In this paper, we focus on the synthesis and characterization of ortho-substituted polyanhydrides, poly[1,3-bis(o-carboxyphenoxy)propane anhydride] (o-CPP) and poly[1,6-bis(o-carboxyphenoxy) hexane anhydride] (p-CPH). By lengthening the alkyl chain between aryl groups (from propane to hexane) and changing the ring substitution pattern from para- to ortho-, we observed enhanced solubility of aromatic polyanhydrides. Ultimately, these polyanhydrides may be useful as polymer scaffolds for use as functional soft tissue substitutes.