Semen quality of 1346 healthy men, results from the Chongqing area of southwest China
Semen quality of 1346 healthy men, results from the Chongqing area of southwest China
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DOI：
10.1093/humrep/den399
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发表时间：
2009-02-01
影响因子：
6.1
通讯作者：
Cao, Jia
中科院分区：
文献类型：
--
作者：
Li, Yafei;Lin, Hui;Cao, Jia
2007年对重庆地区1346名健康男性的精液质量进行了横断面调查。测量精液参数并与世界卫生组织（WHO）标准进行比较。采用线性回归模型分析精液质量的决定因素，其中位数分别为：精液量2.3ml，精液浓度77.8 × 10 ~（6）/ml，精子总数167.7 × 10 ~（6），精子快速前向运动率33%，精子前向运动率52.6%，精子总运动率70.9%。根据WHO标准，61.1%的健康男性至少有一项精液参数低于正常阈值。季节和禁欲时间与精液质量显著相关（P < 0.001）。年龄、吸烟、饮酒和BMI对精液参数影响不大或无影响，重庆地区健康男性精液参数异常率较高。研究人群的精液参数与其他中国、美国和欧洲人群报告的精液参数明显不同。这些差异仍然无法解释，可能是由于人口特征，生活方式，环境因素或遗传变异。
Large studies on semen quality of the general healthy population from China are rare.A cross-sectional study was performed to evaluate the semen quality of 1346 healthy men residing in Chongqing area of southwest China in 2007. The semen parameters were measured and compared with the World Health Organization (WHO) criteria. A linear regression model was used to examine the determinants of semen quality.The medians were 2.3 ml for semen volume, 77.8 x 10(6) per ml for semen concentration, 167.7 x 10(6) for total sperm count, 33% for sperm rapid progressive motility, 52.6% for sperm progressive motility and 70.9% for total motility. According to WHO criteria, 61.1% of healthy males had at least one semen parameter below normal threshold values. Season and abstinence duration were found to be significantly associated with semen quality (P < 0.001). Age, smoking, alcohol use and BMI had little or no effect on semen parameters.A high proportion of healthy males in Chongqing area of southwest China had abnormal semen parameters values according to WHO criteria. The semen parameters in the study population were markedly different from those reported for the other Chinese, USA and European populations. The differences remain unexplained and may be due to demographic characteristics, lifestyle, environmental factors or genetic variation.