PROGRESSIVE CHROMOSOME CHANGES ASSOCIATED WITH DIFFERENT SITES OF ONE OVARIAN-CARCINOMA
PROGRESSIVE CHROMOSOME CHANGES ASSOCIATED WITH DIFFERENT SITES OF ONE OVARIAN-CARCINOMA
复制标题
DOI：
10.1093/jnci/66.6.1021
复制
发表时间：
1981-01-01
影响因子：
10.3
通讯作者：
EDWARDS, CL
中科院分区：
文献类型：
--
作者：
KUSYK, CJ;SESKI, JC;EDWARDS, CL
对原发部位和转移部位的细胞以及 1 名卵巢浆液性癌患者的腹水进行了核型分析。近四倍体细胞比例的增加按以下顺序发生：来自原发部位的细胞少于来自转移部位的细胞少于来自腹水的细胞。腹水多倍体细胞中出现了两条新的标记染色体。
Karyotype analyses were done on cells from the primary and metastatic sites, and on the ascitic fluid from 1 patient with serous carcinoma of the ovary. An increase in the proportion of near-tetraploid cells occurred in the following order: cells from the primary site less than cells from the metastatic site less than cells from ascitic fluid. Two new marker chromosomes appeared among the polyploid cells of ascitic fluid.