Volumes of the caudate nuclei in women with somatization disorder and healthy women
Volumes of the caudate nuclei in women with somatization disorder and healthy women
复制标题
DOI：
10.1016/j.pscychresns.2004.03.001
复制
发表时间：
2004-05-30
影响因子：
2.3
通讯作者：
Niemi, PM
中科院分区：
文献类型：
--
作者：
Hakala, M;Karlsson, H;Niemi, PM
我们对躯体化障碍的病理生理学知之甚少。本研究旨在通过对这些患者大脑葡萄糖代谢的观察，分析一些可能参与躯体化的大脑结构的体积。我们研究了10例诊断为躯体化障碍或未分化躯体形式障碍且未合并DSM-IV -I轴障碍的女性患者，并使用脑MRI （1.5T仪器）将其与16名健康女性志愿者进行比较。与健康志愿者相比，患者双侧尾状核体积增大。这些尾状核的体积差异可能与躯体化的病理生理有关。2004爱思唯尔爱尔兰有限公司版权所有。
Very little is known about the pathophysiology of somatization disorder. This study was designed to analyze the volumes of some brain structures possibly involved in somatization based on the observation of glucose metabolism of the brain in these patients. We studied 10 female patients with a diagnosis of somatization disorder or undifferentiated somatoform disorder with no comorbid current DSM-IV Axis I disorder and compared them to 16 healthy female volunteers using brain MRI (1.5T instrument). The patients had bilateral enlargement of caudate nuclei volumes compared with healthy volunteers. These volume differences in the caudate nuclei could be associated with the pathophysiology of somatization. (C) 2004 Elsevier Ireland Ltd. All rights reserved.