Development of the two Korean adult tomographic computational phantoms for organ dosimetry
Development of the two Korean adult tomographic computational phantoms for organ dosimetry
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DOI：
10.1118/1.2161405
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发表时间：
2006-02-01
期刊：
影响因子：
3.8
通讯作者：
Lee, JK
中科院分区：
文献类型：
--
作者：
Lee, C;Lee, C;Lee, JK
继先前开发的韩国断层扫描幻影，KORMAN，两个额外的全身断层扫描幻影韩国成年男性的磁共振（MR）和计算机断层扫描（CT）图像，分别开发。招募了两名健康男性志愿者，他们的身体尺寸相当代表韩国成年男性的平均水平，并对其进行了体模扫描。从一名受试者（不包括手臂）获得连续的全身MR图像，而从第二名受试者获得全身CT图像。通过灰度阈值、区域生长和手动绘图等图像处理技术对总共29个器官和组织以及19个骨骼部位进行分割，其中每个分割的图像切片随后由经验丰富的放射科医生进行解剖准确性审查。得到的体模，基于MR的KTMAN-1（韩国典型MAN-1）和基于CT的KTMAN-2（韩国典型MAN-2），由300 X 150 X 344体素组成，两个体模的体素分辨率为2 X 2 X 5 mm（3）。分割器官和组织的质量计算为标称参考密度、前体素体积和定义每个器官或组织的体素累积数量的乘积。然后将这些器官质量与亚洲和ICRP参考成年男性的器官质量进行比较。KTMAN-1和KTMAN-2中的器官质量显示出在亚洲和ICRP参考值的40%内的差异，皮肤、胆囊和胰腺除外，其显示出较大的差异。将所得三维二进制文件移植到蒙特卡罗代码MCNPX 2.4中，以计算外照射后的器官剂量，用于说明目的。结肠，肺，肝，胃吸收剂量，以及有效剂量，为理想化的光子照射几何形状（前后和右侧）进行了测定，然后与其他两个断层幻影（亚洲人和高加索人），和程式化的ORNL幻影的数据进行了比较。无臂KTMAN-1可用于计算机断层扫描或侧位X射线检查的剂量测定，而全身KTMAN-2可用于辐射防护剂量测定。(c)2006年美国医学物理学家协会。
Following the previously developed Korean tomographic phantom, KORMAN, two additional whole-body tomographic phantoms of Korean adult males were developed from magnetic resonance (MR) and computed tomography (CT) images, respectively. Two healthy male volunteers, whose body dimensions were fairly representative of the average Korean adult male, were recruited and scanned for phantom development. Contiguous whole body MR images were obtained from one subject exclusive of the arms, while whole-body CT images were acquired from the second individual. A total of 29 organs and tissues and 19 skeletal sites were segmented via image manipulation techniques such as gray-level thresholding, region growing, and manual drawing, in which each of segmented image slice was subsequently reviewed by an experienced radiologist for anatomical accuracy. The resulting phantoms, the MR-based KTMAN-1 (Korean Typical MAN-1) and the CT-based KTMAN-2 (Korean Typical MAN-2), consist of 300 X 150 X 344 voxels with a voxel resolution of 2 X 2 X 5 mm(3) for both phantoms. Masses of segmented organs and tissues were calculated as the product of a nominal reference density, the prevoxel volume, and the cumulative number of voxels defining each organs or tissue. These organs masses were then compared with those of both the Asian and the ICRP reference adult male. Organ masses within both KTMAN-1 and KTMAN-2 showed differences within 40% of Asian and ICRP reference values, with the exception of the skin, gall bladder, and pancreas which displayed larger differences. The resulting three-dimensional binary file was ported to the Monte Carlo code MCNPX2.4 to calculate organ doses following external irradiation for illustrative purposes. Colon, lung, liver, and stomach absorbed doses, as well as the effective dose, for idealized photon irradiation geometries (anterior-posterior and right lateral) were determined, and then compared with data from two other tomographic phantoms (Asian and Caucasian), and stylized ORNL phantom. The armless KTMAN-1 can be applied to dosimetry for computed tomography or lateral x-ray examination, while the whole body KTMAN-2 can be used for radiation protection dosimetry. (c) 2006 American Association of Physicists in Medicine.