The incidence of drugs in drivers killed in Australian road traffic crashes

The incidence of drugs in drivers killed in Australian road traffic crashes
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DOI:
10.1016/s0379-0738(03)00134-8
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发表时间:
2003-07-08
影响因子:
2.2
通讯作者:
Swann, P
Swann, P
中科院分区:
医学3区
文献类型:
--
作者:
Drummer, OH;Gerostamoulos, J;Swann, P

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在澳大利亚的三个州确定了致命受伤司机的酒精和药物发生率; 1990-1999 年期间维多利亚州 (VIC)、新南威尔士州 (NSW) 和西澳大利亚州 (WA)。共调查了 3398 名司机死亡事件,其中包括 2609 名汽车司机、650 名摩托车司机和 139 名卡车司机。 29.1% 的驾驶员体内酒精含量达到或超过 0.05 克/100 毫升 (%)。患病率最高的是汽车司机(30.3%),最低的是卡车司机(8.6%)。西澳州的饮酒率是这三个州中最高的(35.8%)。近 10% 的案件涉及酒精和毒品。 26.7% 的病例中存在药物(酒精除外),23.5% 的病例中存在精神药物。这些药物包括大麻(13.5%)、阿片类药物(4.9%)、兴奋剂(4.1%)、苯二氮卓类药物(4.1%)和其他精神药物(2.7%)。 8.5% 的所有司机检测呈 Delta(9)-四氢大麻酚 (THC) 阳性,其余大麻阳性司机仅对 11-正-Delta(9)-四氢大麻酚-9-羧酸(羧基-THC)代谢物呈阳性。驾驶员的 THC 血液浓度范围为 0.1-228 ng/ml,中位数为 9 ng/ml。阿片类药物主要包括吗啡(n = 84)、可待因(n = 89)和美沙酮(n = 33),而兴奋剂主要包括甲基苯丙胺(n = 51)、摇头丸(n = 6)、可卡因(n = 5)和麻黄碱(n = 61)。十年来,毒品流行率有所上升,特别是大麻和阿片类药物,而酒精则有所下降。摩托车手中吸食大麻的比例更高(22.2%),而卡车司机中吸食兴奋剂的比例则要高得多(23%)。 (C) 2003 Elsevier Science Ireland Ltd. 保留所有权利。
The incidence of alcohol and drugs in fatally injured drivers were determined in three Australian states; Victoria (VIC), New South Wales (NSW) and Western Australia (WA) for the period of 1990-1999. A total of 3398 driver fatalities were investigated which included 2609 car drivers, 650 motorcyclists and 139 truck drivers. Alcohol at or over 0.05 g/100 ml (%) was present in 29.1% of all drivers. The highest prevalence was in car drivers (30.3%) and the lowest in truckers (8.6%). WA had the highest rate of alcohol presence of the three states (35.8%). Almost 10% of the cases involved both alcohol and drugs. Drugs (other than alcohol) were present in 26.7% of cases and psychotropic drugs in 23.5%. These drugs comprised cannabis (13.5%), opioids (4.9%), stimulants (4.1%), benzodiazepines (4.1%) and other psychotropic drugs (2.7%). 8.5% of all drivers tested positive for Delta(9)-tetrahydrocannabinol (THC) and the balance of cannabis positive drivers were positive to only the 11-nor-Delta(9)-tetrahydrocannabinol-9-carboxylic acid (carboxy-THC) metabolite. The range of THC blood concentrations in drivers was 0.1-228 ng/ml, with a median of 9 ng/ml. Opioids consisted mainly of morphine (n = 84), codeine (n = 89) and methadone (n = 33), while stimulants consisted mainly of methamphetamine (n = 51), MDMA (n = 6), cocaine (n = 5), and the ephedrines (n = 61). The prevalence of drugs increased over the decade, particularly cannabis and opioids, while alcohol decreased. Cannabis had a larger prevalence in motorcyclists (22.2%), whereas stimulants had a much larger presence in truckers (23%). (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.