Isotope effect on the solubility of amino acids in water
Isotope effect on the solubility of amino acids in water
复制标题
同位素对氨基酸在水中溶解度的影响
DOI：
10.1007/bf00972645
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发表时间：
1996
影响因子：
1.2
通讯作者：
J. Szydłowski
中科院分区：
文献类型：
--
作者：
M. Jelińska;J. Szydłowski
测定了甘氨酸、丙氨酸、苯丙氨酸和脯氨酸在283 ~ 335 K范围内的溶解度。结果发现，甘氨酸和丙氨酸是不溶于重水比在轻水，但脯氨酸是更易溶于重水在整个温度范围内的研究。苯丙氨酸在低于310 K时比D2 O更易溶于H2O，但在高于该温度时重水成为更好的溶剂。还观察到了H/D同位素替代对溶液结晶度的影响。在甘氨酸和丙氨酸的情况下，在重水中的溶解焓增加了少量，同时苯丙氨酸在D_2O中的溶解焓显着增加。脯氨酸的溶解焓没有变化。定性地讨论了溶解度和溶解焓的同位素效应。
The solubilities of glycine, alanine, phenylalanine, and proline in H2O and D2O from 283 K to 335 K were determined. It was found that glycine and alanine are less soluble in heavy water than in light water but proline is more soluble in heavy water over the whole temperature range studied. Phenylalanine is more soluble in H2O than D2O below 310 K but above that temperature heavy water becomes a better solvent. An influence of H/D isotope substitution on the enthalpies of solution is also observed. In the case of glycine and alanine enthalpies of solution in heavy water increase by a small amount and in the same time the solution enthalpy for phenylalanine in D2O increases markedly. No change in the solution enthalpy for proline was observed. The isotope effects on solubility and the solution enthalpy are qualitatively discussed.