Prevalence and clinical characteristics of mental rituals in a longitudinal clinical sample of obsessive-compulsive disorder.

Prevalence and clinical characteristics of mental rituals in a longitudinal clinical sample of obsessive-compulsive disorder.
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DOI:
10.1002/da.20869
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发表时间:
2011-10-03
影响因子:
7.4
通讯作者:
Rasmussen, Steven A.
Rasmussen, Steven A.
中科院分区:
医学1区
文献类型:
--
作者:
Sibrava, Nicholas J.;Boisseau, Christina L.;Mancebo, Maria C.;Eisen, Jane L.;Rasmussen, Steven A.

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强迫症(OCD)是一种慢性和衰弱性焦虑症,与生活质量和功能的显著损害相关。研究不同强迫症的临床相关性和治疗反应的差异,得出了重要的发现,强调了这种疾病的异质性。到目前为止,大多数研究都集中在与原发性强迫症相关的差异上,很少注意研究强迫症状如何影响临床过程的临床效用。几乎没有系统的研究探讨了一个未充分研究的症状表现的临床特征,精神仪式,以及这种主要症状对疾病严重程度和病程的影响。精神仪式或没有明显迹象的强迫行为代表了独特的临床挑战,但由于多种方法和临床原因,常常未得到充分研究。在本研究中,我们探讨了主要的精神仪式的临床严重程度和慢性的影响,在一个大的纵向样本的强迫症患者(N = 225)超过4年。精神仪式是一个主要的表现症状的样本(12.9%)的相当大的百分比。主要精神仪式与更大的临床严重程度和摄入时较低的功能以及更慢性的疾病过程相关,因为在4年的随访期间,具有主要精神仪式的参与者在完整的DSM-IV标准发作中比没有精神仪式的强迫症患者多花了近1年的时间。这些结果表明,精神仪式是独特的损害,并强调需要进一步的经验探索和治疗考虑。
Obsessive-compulsive disorder (OCD) is a chronic and debilitating anxiety disorder associated with significant impairment in quality of life and functioning. Research examining the differences in clinical correlates and treatment response associated with different obsessions in OCD has yielded important findings underscoring the heterogeneous nature of this disorder. To date, most of this research has focused on differences associated with primary obsessions, and little attention has been paid to the clinical utility of studying how compulsive symptoms affect clinical course. Virtually no systematic research has explored the clinical characteristics of one understudied symptom presentation, mental rituals, and what impact this primary symptom has on severity and course of illness. Mental rituals, or compulsions without overt signs, represent unique clinical challenges but often go understudied for numerous methodological and clinical reasons. In the present study, we explored the impact of primary mental rituals on clinical severity and chronicity in a large, longitudinal sample of OCD patients (N = 225) over 4 years. Mental rituals were a primary presenting symptom for a sizable percentage of the sample (12.9%). Primary mental rituals were associated with greater clinical severity and lower functioning at intake, as well as a more chronic course of illness, as participants with primary mental rituals spent nearly 1 year longer in full DSM-IV criteria episodes over the 4-year follow-up interval than OCD patients without mental rituals. These results suggest that mental rituals are uniquely impairing and highlight the need for further empirical exploration and consideration in treatment.
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