Risk factors for hemorrhagic stroke in Wonju, Korea
Risk factors for hemorrhagic stroke in Wonju, Korea
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DOI：
10.3349/ymj.1998.39.3.229
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发表时间：
1998-06-01
影响因子：
2.4
通讯作者：
Koh, SY
中科院分区：
文献类型：
--
作者：
Park, JK;Kim, HJ;Koh, SY
虽然中风在韩国是一个巨大的公共卫生挑战，但很少有关于中风危险因素的流行病学研究。在韩国元州进行了一项病例对照研究，以评价出血性卒中的危险因素。1994年至1995年期间，在元州基督教医院的住院患者中招募了95例蛛网膜下腔出血（SAH）和102例脑出血（ICH）患者，年龄21岁至86岁，以及267例对照。资料是通过面谈和考试收集的。校正年龄和性别后，高血压家族史和既往史、饮酒习惯、初潮年龄、身高、体重、体重指数、腰围和臀围、耳垂皱褶、凝血酶原时间、白色血细胞计数、血红蛋白和总胆固醇均与SAH和ICH显著相关。仅与ICH显著相关的风险因素是吸烟习惯。在多因素Logistic分析中，SAH和ICH的独立危险因素是相同的。包括高血压家族史、既往史、初潮年龄、耳垂皱褶、凝血酶原时间、白色血细胞计数、血红蛋白和总胆固醇。除吸烟外，SAH和ICH的危险因素基本相似。本研究发现的危险因素与以前的研究一致，包括高血压家族史和既往史、饮酒习惯、体重指数、凝血酶原时间、白色血细胞计数和血红蛋白。那些不一致的或更确切地说是新发现的是初潮年龄、大体格、耳垂皱纹和总胆固醇。
Although stroke is a great public health challenge in Korea, there have been few epidemiologic studies of the risk factors for stroke. A case-control study was performed to evaluate the risk factors for hemorrhagic stroke in Wonju, Korea. Ninety-five subarachnoid hemorrhage (SAH) and 102 intracerebral hemorrhage (ICH) patients aged 21 similar to 86 years, and 267 controls were recruited among the inpatients of Wonju Christian Hospital during 1994 similar to 1995. Information was gathered through interviews and examinations. After adjustment for age and sex, family and past history of hypertension, drinking habits, age of menarche, height, weight, body mass index, waist and hip circumference, earlobe crease, prothrombin time, white blood cell count, hemoglobin, and total cholesterol were all found to be significantly associated with both SAH and ICH. The risk factor significantly associated only with ICH was smoking habits. In multiple logistic analyses, the independent risk factors for SAH and ICH were the same. Those included family and past history of hypertension, age of menarche, earlobe crease, prothrombin time, white blood cell count, hemoglobin and total cholesterol. In general, the risk factors for SAH and ICH were similar with each other, except smoking habits. Risk factors found in this study congruent with previous studies were family and past history of hypertension, drinking habits, body mass index, prothrombin time, white blood cell count, and hemoglobin. Those incongruent or rather newly found were age of menarche, a big physique, earlobe crease, and total cholesterol.