Echo intensity obtained from ultrasonography images reflecting muscle strength in elderly men.
Echo intensity obtained from ultrasonography images reflecting muscle strength in elderly men.
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DOI：
10.2147/cia.s47263
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发表时间：
2013
影响因子：
3.6
通讯作者：
Kimura M
中科院分区：
文献类型：
--
作者：
Watanabe Y;Yamada Y;Fukumoto Y;Ishihara T;Yokoyama K;Yoshida T;Miyake M;Yamagata E;Kimura M
众所周知，肌肉质量的损失（量变）是随着衰老而发生的主要变化。随着年龄的增长，骨骼肌也会发生质的变化，例如肌内脂肪增加。骨骼肌超声图像上的增强回波强度（EI）被认为反映了肌肉质量。最近使用计算机辅助灰度分析评估骨骼肌质量的研究表明，EI 与中老年女性的肌肉力量无关，与年龄或肌肉大小无关。本研究的目的是调查老年男性基于 EI 的肌肉质量是否与肌肉力量相关，而与肌肉大小无关。共有 184 名独立生活在日本京都的老年男性（65-91 岁）参与了这项研究。通过评估超声图像确定右大腿前室的 EI、肌肉厚度 (MT) 和皮下脂肪厚度 (FT)。测量膝关节角度为 90° 时膝关节伸展的最大等长扭矩。 EI与肌肉力量呈显着负相关（r = -0.333，P < 0.001）。多变量回归分析显示，伸膝肌的 MT 和 EI 与最大等长伸膝力量独立相关。即使以年龄、身高、体重和 FT 作为控制变量进行偏相关分析，EI 仍然与肌肉力量显着相关。这项研究的结果表明，与衰老相关的肌肉质量变化会导致肌肉力量减弱。超声检查是一种低成本、易于使用且安全的方法，适合评估 EI 作为肌肉质量的指标。
It is well known that loss of muscle mass (quantitative change) is a major change that occurs with aging. Qualitative changes in skeletal muscle, such as increased intramuscular fat, also occur as one ages. Enhanced echo intensity (EI) on ultrasonography images of skeletal muscle is believed to reflect muscle quality. Recent studies evaluating the quality of skeletal muscle using computer-aided gray scale analysis showed that EI is associated with muscle strength independently of age or muscle size in middle-aged and elderly women. The aim of the present study was to investigate whether muscle quality based on EI is associated with muscle strength independently of muscle size for elderly men. A total of 184 elderly men (65–91 years) living independently in Kyoto, Japan, participated in this study. The EI, muscle thickness (MT), and subcutaneous fat thickness (FT) of the anterior compartment of the right thigh were determined by assessing ultrasonography images. The maximum isometric torque of knee extension at a knee angle of 90° was measured. The EI showed a significant negative correlation with muscle strength (r = −0.333, P < 0.001). Multivariate regression analysis revealed that the MT and EI of the knee extensor muscle were independently associated with maximum isometric knee extension strength. Even when partial correlation analysis was performed with age, height, weight, and FT as control variables, EI was still significantly correlated with muscle strength. The results of this study indicate that aging-related changes in muscle quality contribute to diminishing muscle strength. Ultrasonography is a low-cost, easily accessible, and safe method suitable for the assessment of EI as an index of muscle quality.