PRESENCE OF MITOCHONDRIAL LARGE RIBOSOMAL-RNA OUTSIDE MITOCHONDRIA IN GERM PLASM OF DROSOPHILA-MELANOGASTER
PRESENCE OF MITOCHONDRIAL LARGE RIBOSOMAL-RNA OUTSIDE MITOCHONDRIA IN GERM PLASM OF DROSOPHILA-MELANOGASTER
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DOI：
10.1126/science.7684857
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发表时间：
1993-06-04
期刊：
影响因子：
56.9
通讯作者：
OKADA, M
中科院分区：
文献类型：
--
作者：
KOBAYASHI, S;AMIKURA, R;OKADA, M
Mitochondrial large ribosomal RNA (mtlrRNA) has been identified as a cytoplasmic factor that induces pole cell formation in embryos whose ability to form a germ line has been abolished by treatment with ultraviolet light. In situ hybridization analyses reveal that mtlrRNA is enriched in germ plasm and is tightly associated with polar granules, the distinctive organelles of germ plasm, which supports the idea that mtlrRNA functions in pole cell formation. This suggests that a product from the mitochondrial genome, along with nuclear products, participates in a key event in embryonic development: determination of the germ line.
