Phenomenology and co-morbidity of childhood onset obsessive compulsive disorder
Phenomenology and co-morbidity of childhood onset obsessive compulsive disorder
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DOI：
10.1024/1422-4917.35.1.41
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发表时间：
2007-01-01
影响因子：
1.2
通讯作者：
Warnke, Andreas
中科院分区：
文献类型：
--
作者：
Jans, Thomas;Wewetzer, Christoph;Warnke, Andreas
目的：为了解儿童青少年强迫症的内容和共病特征，对55例儿童青少年强迫症患者进行调查，其中男29例，女26例，主要来自大学儿童青少年精神科门诊，占95%。结构化诊断访谈被用来采访病人和他们的父母。结果：平均发病年龄为强迫症是11.3岁。在男性中，发病略早于女性，但这种差异并不显著。主要是指洗涤和清洁，检查，重复，排序和计数。最常见的强迫观念包括对污染、灾难、性和攻击性的思考。根据父母的报告，合并症的发生率很高（终生诊断：69%，当前诊断：53%），焦虑、抑郁、多动症、行为和饮食障碍是最常见的合并症。那些一生中被诊断患有其他精神疾病的患者的强迫症状更严重。结构化访谈时发现的比率进行了比较，根据研究协议的临床医生，临床医生被发现诊断混合强迫症的想法和行为（呈现强迫症的想法，以及强迫行为）的频率较低。结论：这项调查的结果是符合国际研究的强迫症。发现的疾病的发生率取决于所使用的诊断方法。一个潜在的有前途的方法，进一步调查是根据症状的尺寸分型的患者。
Objectives: The goal of the study was to investigate the contents and comorbidity features of obsessive-compulsive disorder in children and adolescents.Method: 55 patients (29 males, 26 females), mainly inpatients selected from university clinics for child and adolescent psychiatry (95%), were investigated. Structured diagnostic interviews were used to interview patients and their parents.Results: The mean age of onset for obsessive-compulsive disorders was 11.3 years. In males the onset was slightly earlier than among females, but this difference was not significantly significant. Compulsions mostly referred to washing and cleaning, checking, repeating, ordering, and counting. Most frequently, obsessions included thought about contamination, catastrophes, sexuality, and aggression. According to parental reports, the rate of comorbidity was high (lifetime diagnosis: 69%, current diagnosis: 53%), with anxiety, depressive, hyperkinetic, conduct, and eating disorders being the most frequent co-morbid conditions. Obsessive-compulsive symptoms were more intense in those patients who had a greater number of lifetime diagnoses of other psychiatric disorders. Comparing the rates found when structured interviews were carried out according to the study protocol to those for clinicians, clinicians were found to have diagnosed mixed obsessional thoughts and acts (presenting obsessional thoughts, as well as compulsive acts) less frequently.Conclusions: The results of this investigation are well in line with those of international studies on obsessive-compulsive disorders. The rates of disorders found were dependent on the diagnostic methods used. A potentially promising approach for further investigation is the sub-typing of patients according to symptom dimensions.