A MALARIA CONTROL TRIAL USING INSECTICIDE-TREATED BED NETS AND TARGETED CHEMOPROPHYLAXIS IN A RURAL AREA OF THE GAMBIA, WEST-AFRICA .2. MORTALITY AND MORBIDITY FROM MALARIA IN THE STUDY AREA
A MALARIA CONTROL TRIAL USING INSECTICIDE-TREATED BED NETS AND TARGETED CHEMOPROPHYLAXIS IN A RURAL AREA OF THE GAMBIA, WEST-AFRICA .2. MORTALITY AND MORBIDITY FROM MALARIA IN THE STUDY AREA
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DOI：
10.1016/0035-9203(93)90170-u
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发表时间：
1993-06-01
影响因子：
2.2
通讯作者：
GREENWOOD, BM
中科院分区：
文献类型：
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作者：
ALONSO, PL;LINDSAY, SW;GREENWOOD, BM
有关疟疾儿童死亡率和发病率的背景数据是在冈比亚中部河流以南的一个新研究区获得的，该研究区被选为疟疾干预试验的地点。婴儿和儿童死亡率分别为每 1000 人 120 例和 41 例。尸检调查问卷得出的结果表明，疟疾是 1 岁以下儿童不常见的死亡原因，但约 40% 的 1-4 岁儿童死亡由疟疾造成。百分之九十二的疟疾死亡发生在雨季期间或雨季之后。疟疾传播季节结束时1-5岁儿童的寄生虫率和脾脏率分别为66%和64%。在初级卫生保健 (PHC) 村庄和较小的非初级卫生保健 (PHC) 对照村庄中，疟疾测定指数相似，这些村庄被选为使用杀虫剂处理的蚊帐和有针对性的化学预防进行干预的地点。
Background data on child mortality and morbidity from malaria were obtained in a new study area in the centre of The Gambia, south of the river, chosen as the site for a malaria intervention trial. Infant and child mortality rates were 120 and 41 per 1000 respectively. Results obtained using post-mortem questionnaires suggested that malaria was an uncommon cause of death in children under the age of one year but responsible for about 40% of deaths in children aged 1-4 years. Ninety-two percent of deaths attributed to malaria occurred during or immediately after the rainy season. Parasite and spleen rates in children aged 1-5 years at the end of the malaria transmission season were 66% and 64% respectively. Malariometric indices were similar in primary health care (PHC) villages, selected as sites for an intervention with insecticide-treated bed nets and targeted chemoprophylaxis, and in smaller, non-PHC, control villages.