International expert panel on the use of primary (Preoperative) systemic treatment of operable breast cancer: Review and recommendations
International expert panel on the use of primary (Preoperative) systemic treatment of operable breast cancer: Review and recommendations
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DOI：
10.1200/jco.2003.01.136
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发表时间：
2003-07-01
影响因子：
45.3
通讯作者：
Senn, HJ
中科院分区：
文献类型：
--
作者：
Kaufmann, M;von Minckwitz, G;Senn, HJ
原发性全身治疗（PST）代表了局部晚期乳腺癌患者的标准治疗。此外，关于可手术乳腺疾病的PST的信息越来越多，支持在常规实践中使用PST。然而，目前的治疗方案和技术各不相同。为了解决这一问题，一组来自法国、德国、意大利、英国和美国乳腺癌临床研究小组的代表回顾了在这种情况下所有可获得的前瞻性随机试验数据。建议包括术语、适应症、治疗方案、治疗前诊断、疗效监测、肿瘤定位、手术、病理评估和术后治疗。(C) 2003年由美国临床肿瘤学会出版。
Primary systemic therapy (PST) represents the standard of care in patients with locally advanced breast cancer. In addition, there is increasing information on PST in operable breast disease that supports the use of PST in routine practice. However, current regimens and techniques vary. To address this concern, a group of representatives from breast cancer clinical research groups in France, Germany, Italy, the United Kingdom, and the United States reviewed all available data on prospective randomized trials in this setting. Recommendations are made regarding terminology, indications, regimen, diagnosis before treatment, monitoring of efficacy, tumor localization, surgery, pathologic evaluation, and postoperative treatment. (C) 2003 by American Society of Clinical Oncology.