The interplay of psychosis and victimisation across the life course: a prospective study in the general population
The interplay of psychosis and victimisation across the life course: a prospective study in the general population
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DOI：
10.1007/s00127-017-1430-9
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发表时间：
2017-11-01
影响因子：
4.4
通讯作者：
Os, Jim van
中科院分区：
文献类型：
--
作者：
Honings, Steven;Drukker, Marjan;Os, Jim van
精神病与成人受害有关。然而，目前尚不清楚是否精神病预测事件的成人mammisation，或是否成人mammisation预测事件的精神病。此外，儿童期抑郁对精神病和成人期抑郁之间的关联的调节作用尚未被研究，基线精神病经历和6年的成人期抑郁发病率之间的纵向关联在一个前瞻性的一般人群队列中进行了评估，6646名成年人使用logistic回归分析。基线成人精神病发作和6年精神病发作率之间的关系也被研究。此外，这些双向协会的调节作用的童年embrisation进行了分析。精神病的经验和童年embrisation都与成人embrisation事件的风险增加。然而，这是通过竞争的途径，精神病经历和童年期的自我反省之间的负面相互作用表明。基线成人精神病发作和儿童精神病发作都独立增加精神病事件的风险，但成人精神病发作和儿童精神病发作之间没有相互作用。精神病和精神病发作在整个生命过程中是相互联系的。儿童期的再发病通过两条途径与精神病联系在一起：一条是直接途径，另一条是通过成人期的再发病间接途径。在没有儿童期痴呆的个体中，精神病和成人期痴呆相互双向影响。
Psychosis has been associated with adult victimisation. However, it remains unclear whether psychosis predicts incident adult victimisation, or whether adult victimisation predicts incident psychosis. Furthermore, a moderating effect of childhood victimisation on the association between psychosis and adult victimisation has not been investigated.The longitudinal association between baseline psychotic experiences and six-year incidence of adult victimisation was assessed in a prospective general population cohort of 6646 adults using logistic regression analysis. The association between baseline adult victimisation and six-year incidence of psychotic experiences was examined as well. Furthermore, the moderating effect of childhood victimisation on these bidirectional associations was analysed.Psychotic experiences and childhood victimisation were both associated with an increased risk of incident adult victimisation. However, this was through competing pathways, as suggested by a negative interaction between psychotic experiences and childhood victimisation. Baseline adult victimisation and childhood victimisation both independently increased the risk of incident psychotic experiences, but there was no interaction between adult victimisation and childhood victimisation.Psychosis and victimisation are interconnected throughout the life course. Childhood victimisation is connected to psychosis through two pathways: one direct and one indirect through adult victimisation. In individuals without childhood victimisation, psychosis and adult victimisation bidirectionally impact on each other.